⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121281 | 1.00 | — | — | |
| SCHEMBL121282 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL18270772 | 0.97 | — | — | |
| SCHEMBL1105059 | 0.84 | — | — | |
| SCHEMBL1105058 | 0.84 | — | — | |
| SCHEMBL2785455 | 0.84 | — | — | |
| SCHEMBL12611124 | 0.82 | — | — | |
| SCHEMBL29101472 | 0.76 | — | — | |
| SCHEMBL27426780 | 0.74 | — | — | |
| SCHEMBL14830432 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122094678-A | AP 2-related kinase 1 inhibitors and uses thereof | — | 2026-05-26 | — | — | CN | disclosed |
| CN-117024411-B | Isoquinoline as HPK1 inhibitor | 豪夫迈·罗氏有限公司 | 2026-05-19 | — | — | CN | disclosed |
| EP-4638446-A1 | THIADIAZOLE DERIVATIVES AS INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | Ventus Therapeutics U.S., Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| EP-4396183-B1 | SUBSTITUTED S-ALANINATE DERIVATIVES | BAYER AG (DE) | 2025-09-03 | — | — | EP | disclosed |
| US-20250270222-A1 | AP2 ASSOCIATED KINASE 1 INHIBITORS AND USES THEREOF | SATELLOS BIOSCIENCE INC. (CA) | 2025-08-28 | — | — | US | disclosed |
| WO-2025136811-A1 | CHEMICAL COMPOUNDS AND USES THEREOF | IDEAYA BIOSCIENCES, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| US-20250122207-A1 | AP2 ASSOCIATED KINASE 1 INHIBITORS AND USES THEREOF | SATELLOS BIOSCIENCE INC. (CA) | 2025-04-17 | — | — | US | disclosed |
| WO-2025054448-A1 | AP2 ASSOCIATED KINASE 1 INHIBITORS AND USES THEREOF | SATELLOS BIOSCIENCE INC. (CA) | 2025-03-13 | — | — | WO | disclosed |
| US-20250074881-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2025-03-06 | — | — | US | disclosed |
| US-20250002483-A1 | SUBSTITUTED S-ALANINATE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2025-01-02 | — | — | US | disclosed |
| EP-0958290-A1 | 1,4-DIHYDROPYRIDIN DERIVATIVES AND THEIR USE IN THERAPY | LABORATOIRE L. LAFON (FR) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998031680-A1 | 1,4-DIHYDROPYRIDIN DERIVATIVES AND THEIR USE IN THERAPY | LABORATOIRE L. LAFON (FR) | 1998-07-23 | — | — | WO | disclosed |
| US-4794186-A | CEPHALOSPORINS INTERMEDIATES | TANABE SEIYAKU CO., LTD. (JP) | 1988-12-27 | — | — | US | disclosed |
| EP-0147181-A2 | Thiazolylacetic acid derivatives and their preparation | Tanabe Seiyaku Co., Ltd. (JP) | 1985-07-03 | — | — | EP | disclosed |
| EP-0057846-B1 | PYRROLIDINE DERIVATIVE, PROCESS AND INTERMEDIATES FOR ITS PREPARATION AND MEDICAMENTS CONTAINING IT | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-06-05 | — | — | EP | disclosed |
| US-4461906-A | IMPROVING INTELLECTUAL CAPACITY | HOFFMANN-LA ROCHE INC. (US) | 1984-07-24 | — | — | US | disclosed |
| US-4452807-A | CENTRAL NERVOUS SYSTEM DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1984-06-05 | — | — | US | disclosed |
| EP-0024030-B1 | PYRROLIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-03-30 | — | — | EP | disclosed |
| EP-0057846-A1 | Pyrrolidine derivative, process and intermediates for its preparation and medicaments containing it | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-08-18 | — | — | EP | disclosed |
| EP-0024030-A1 | Pyrrolidine derivatives, processes for their preparation and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-02-18 | — | — | EP | disclosed |