Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3219212 | 1.00 | TACR1 (0.50) | TACR1MRGPRX1DRD4TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8988244 | 0.82 | CHRNA7 (0.49) | TACR1MRGPRX1CHRNA7CHRM2CHRM4 | |
| SCHEMBL8988424 | 0.81 | CHRNA7 (0.51) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3219324 | 0.81 | MEN1 (0.51) | TACR1CHRNA7CHRM2CHRM4CHRM5 | |
| SCHEMBL3216580 | 0.81 | CYP1A2 (0.54) | TACR1DRD4TMEM97SIGMAR1CHRNA7 | |
| SCHEMBL3210424 | 0.81 | GLA (0.54) | TACR1CHRNA7CHRM2CHRM4CHRM5 | |
| SCHEMBL3210416 | 0.81 | GLA (0.54) | TACR1CHRNA7CHRM2CHRM4CHRM5 | |
| SCHEMBL3216566 | 0.81 | CYP1A2 (0.54) | TACR1DRD4TMEM97SIGMAR1CHRNA7 | |
| SCHEMBL3219330 | 0.81 | MEN1 (0.51) | TACR1CHRNA7CHRM2CHRM4CHRM5 | |
| SCHEMBL3218557 | 0.80 | CHRNA7 (0.58) | CHRNA7CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056565-A1 | Heterocyclic Derivatives as M3 Muscarinic Receptors | ARGENTA DISCOVERY LIMITED (GB) | 2010-03-04 | — | — | US | disclosed |
| EP-2121688-A1 | HETEROCYCLIC DERIVATIVES AS M3 MUSCARINIC RECEPTORS | Argenta Discovery Ltd (GB) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008099186-A1 | HETEROCYCLIC DERIVATIVES AS M3 MUSCARINIC RECEPTORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056565-A1 | Heterocyclic Derivatives as M3 Muscarinic Receptors | CHRM2, CHRM3, CHRM1 | TACR1 54/4885MRGPRX1 31/4885DRD4 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.