Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17147918 | 0.96 | TSHR (0.65) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL14243837 | 0.88 | TSHR (0.56) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL278196 | 0.87 | TSHR (0.64) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL244114 | 0.87 | TSHR (0.95) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL6359732 | 0.86 | TSHR (0.64) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9101988 | 0.84 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL13945622 | 0.84 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Ethylene SCHEMBL977945 | 0.84 | TSHR (0.90) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8493780 | 0.84 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL322713 | 0.84 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834126-B2 | Amide-containing polymers for rheology control | BYK-CHEMIE GMBH (DE) | 2010-11-16 | — | — | US | disclosed |
| US-7799890-B2 | Amide-containing polymers for rheology control | BYK-CHEMIE GMBH (DE) | 2010-09-21 | — | — | US | disclosed |
| US-20080132671-A1 | AMIDE-CONTAINING POLYMERS FOR RHEOLOGY CONTROL | BYK-CHEMIE GMBH | 2008-06-05 | — | — | US | disclosed |
| US-20070088148-A1 | Amide-containing polymers for rheology control | BYK-CHEMIE GMBH (DE) | 2007-04-19 | — | — | US | disclosed |