Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1297181 | 0.87 | TP53 (0.41) | CYP3A4TP53GAARAB9ASMN1; SMN2 | |
| SCHEMBL1296803 | 0.87 | TP53 (0.43) | CYP3A4TP53GAARAB9ASMN1; SMN2 | |
| SCHEMBL780426 | 0.87 | TP53 (0.46) | CYP3A4TP53GAARAB9ASMN1; SMN2 | |
| SCHEMBL1296083 | 0.86 | TP53 (0.40) | CYP3A4TP53GAARAB9ASMN1; SMN2 | |
| SCHEMBL2838414 | 0.86 | TP53 (0.40) | BLMLMNAPTPN1CYP3A4TP53 | |
| SCHEMBL782037 | 0.85 | TP53 (0.42) | CYP3A4TP53GAARAB9ASMN1; SMN2 | |
| SCHEMBL1296648 | 0.84 | TP53 (0.39) | CYP3A4TP53GAARAB9ASMN1; SMN2 | |
| SCHEMBL1296675 | 0.84 | TP53 (0.39) | CYP3A4TP53GAARAB9ASMN1; SMN2 | |
| SCHEMBL1297327 | 0.84 | TP53 (0.39) | CYP3A4TP53GAARAB9ASMN1; SMN2 | |
| SCHEMBL1297370 | 0.84 | TP53 (0.39) | CYP3A4TP53GAARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2071010-B1 | GREASE | IDEMITSU KOSAN CO (JP) | 2019-08-07 | — | — | EP | disclosed |
| US-8703678-B2 | Grease | IDEMITSU KOSAN CO., LTD. (JP) | 2014-04-22 | — | — | US | disclosed |
| US-20100035779-A1 | GREASE | IDEMITSU KOSAN CO., LTD (JP) | 2010-02-11 | — | — | US | disclosed |
| EP-2071010-A1 | GREASE | Idemitsu Kosan Co., Ltd. (JP) | 2009-06-17 | — | — | EP | disclosed |