SCHEMBL3222332

SCHEMBL3222332

O=C(O)CCc1ccc2cc3ccccc3cc2c1CCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.50
CYP2D6 P10635 1/20 0.47
CYP2C19 P33261 1/20 0.47
CCNC P24863 1/20 0.46
CDK8 P49336 1/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
POLB P06746 1/20 0.44
FFAR1 O14842 4/20 0.43
KEAP1 Q14145 1/20 0.42
FFAR4 Q5NUL3 2/20 0.41
PTGER1 P34995 1/20 0.41
PTGER4 P35408 1/20 0.41
PTGER3 P43115 1/20 0.41
PTGER2 P43116 1/20 0.41
AKR1B1 P15121 1/20 0.41
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 2/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2992806 0.85 KDM4E (0.56) CYP1A2CYP2D6CYP2C19MEN1KMT2A
SCHEMBL5593879 0.82 PTGER1 (0.51) CYP1A2CYP2D6CYP2C19CCNCCDK8
SCHEMBL30532048 0.81 PTGER1 (0.50) CYP1A2CYP2D6CYP2C19CCNCCDK8
SCHEMBL29684732 0.80 MEN1 (0.53) CYP1A2CYP2D6CYP2C19MEN1KMT2A
SCHEMBL1882693 0.80 MEN1 (0.53) CYP1A2CYP2D6CYP2C19MEN1KMT2A
SCHEMBL31006517 0.77 PARP1 (0.48) CYP1A2CYP2D6CYP2C19MEN1KMT2A
SCHEMBL29113112 0.76 MEN1 (0.60) CYP1A2CYP2D6CYP2C19MEN1KMT2A
SCHEMBL28272845 0.76 BCL2 (0.40) MEN1KMT2APOLBKDM4EALDH1A1
SCHEMBL5953909 0.75 CYP1A2 (0.50) CYP1A2CYP2D6CYP2C19MEN1KMT2A
SCHEMBL20010298 0.73 CYP1A2 (0.59) CYP1A2CYP2D6CYP2C19MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113015482-A Small highly uniform nano-drug compositions for therapeutic, imaging and theranostic applications 密歇根大学董事会 2021-06-22 CN disclosed
EP-1675570-B1 USE OF PHOTODYNAMIC THERAPEUTIC AGENTS ENTRAPPED IN CERAMIC NANOPARTICLES THE RES FOUND OF STATE UNIV OF NEW YORK (US) 2016-12-14 EP disclosed
US-8399168-B2 Method for producing toner, two-component developer, developing device and image forming apparatus SHARP KABUSHIKI KAISHA (JP) 2013-03-19 US disclosed
US-7741001-B2 Toner for electrostatic image development and process for preparing the same SHARP KABUSHIKI KAISHA (JP) 2010-06-22 US disclosed
US-20100055597-A1 METHOD FOR PRODUCING TONER, TWO-COMPONENT DEVELOPER, DEVELOPING DEVICE AND IMAGE FORMING APPARATUS SHARP KABUSHIKI KAISHA (JP) 2010-03-04 US disclosed
US-7572566-B2 humidity resistance, small particle size, less likely to aggregate; for electrophotography; without causing thermal decomposition of a resin or separation of a release agent; applying shear stress to a mixture of a pigmented resin, an organic solvent, a polymer dispersant SHARP KABUSHIKI KAISHA (JP) 2009-08-11 US disclosed
WO-2009038659-A2 ORGANICALLY MODIFIED SILICA NANOPARTICLES WITH COVALENTLY INCORPORATED PHOTOSENSITIZERS FOR DRUG DELIVERY IN PHOTODYNAMIC THERAPY HEALTH RESEARCH, INC. (US) 2009-03-26 WO disclosed
US-7364754-B2 Ceramic based nanoparticles for entrapping therapeutic agents for photodynamic therapy and method of using same RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) 2008-04-29 US disclosed
US-20070042283-A1 Toner for development and method of producing toner SHARP KABUSHIKI KAISHA (JP) 2007-02-22 US disclosed
US-20070020550-A1 Toner for electrostatic image development and process for preparing the same SHARP KABUSHIKI KAISHA (JP) 2007-01-25 US disclosed
US-20060222992-A1 Toner for electrostatic image development and process for preparing the same SHARP KABUSHIKI KAISHA (JP) 2006-10-05 US disclosed
EP-1675570-A2 USE OF PHOTODYNAMIC THERAPEUTIC AGENTS ENTRAPPED IN CERAMIC NANOPARTICLES THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2006-07-05 EP disclosed
US-20040180096-A1 Ceramic based nanoparticles for entrapping therapeutic agents for photodynamic therapy and method of using same RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE 2004-09-16 US disclosed
WO-2004067508-A2 USE OF PHOTODYNAMIC THERAPY THERAPEUTIC AGENTS ENTRAPPED IN CERAMIC NANOPARTICLES THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEWYORK (US) 2004-08-12 WO disclosed