SCHEMBL322241

SCHEMBL322241

Nc1ccncc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29798342 1.00
Formic Acid SCHEMBL28822762 0.87 GAA (0.76)
SCHEMBL29439807 0.79
SCHEMBL760547 0.79
SCHEMBL26920846 0.77 GAA (0.59)
Hydrochloric Acid SCHEMBL14717555 0.77
Hydrochloric Acid SCHEMBL14717645 0.77 GAA (0.62)
SCHEMBL1261588 0.75 AXL (0.60)
SCHEMBL31339925 0.75 GAA (0.59)
SCHEMBL619424 0.75 GAA (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012098070-A1 QUINOLINE DYRK1 INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2012-07-26 WO claimed
US-20120184548-A1 CARBOXYLIC ACID ARYL AMIDES DOMINIQUE ROMYR (US) 2012-07-19 US claimed
CN-101723887-A Preparation and application of N-(3-chloropyridine-4-group)-2-hydroxide group-5-chlorbenzamide LANZHOU MAIDESHENG MEDICAL TEC 2010-06-09 CN claimed
EP-1086106-B1 FUROPYRIDINE DERIVATIVES AND THEIR THERAPEUTICAL USE DARWIN DISCOVERY LTD (GB) 2003-08-20 EP claimed
EP-1086106-A1 FUROPYRIDINE DERIVATIVES AND THEIR THERAPEUTICAL USE Darwin Discovery Limited (GB) 2001-03-28 EP claimed
WO-1999064423-A1 FUROPYRIDINE DERIVATIVES AND THEIR THERAPEUTICAL USE DARWIN DISCOVERY LIMITED (GB) 1999-12-16 WO claimed
CN-119101046-B 3-Naphthyl thiophene derivative, and preparation method and application thereof SHENYANG PHARMACEUTICAL UNIVERSITY (CN) 2026-05-26 CN disclosed
EP-4727940-A1 DIHYDROPYRIMIDINE-2, 4 (1H, 3H) -DIONE-CONTAINING POLYCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREOF AND USE THEREOF Linkcure Therapeutics (KY) 2026-04-22 EP disclosed
US-20260098047-A1 Anti-Giardial Compounds COMMW SCIENT IND RES ORG (AU) 2026-04-09 US disclosed
EP-4720042-A1 COMPOUNDS FOR SIGHT RESTORATION Fundació Institut de Bioenginyeria de Catalunya (IBEC) (ES) 2026-04-08 EP disclosed
EP-4713327-A1 SPIRO DERIVATIVES AS WRN INHIBITORS Insilico Medicine IP Limited (HK) 2026-03-25 EP disclosed
US-12559486-B2 Tau-protein targeting compounds and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-02-24 US disclosed
US-20260049080-A1 WILD TYPE KIT INHIBITORS BLUEPRINT MEDICINES CORP (US) 2026-02-19 US disclosed
US-4628100-A ANTIDEPRESSANTS A. H. ROBINS COMPANY, INCORPORATED (US) 1986-12-09 US disclosed
US-4560510-A CONDENSATION OF AN AMINOCHLOROPYRIDINE WITH A ARYL(AMINOPHENYL)METHANONE WITH A BASE) A. H. ROBINS COMPANY, INCORPORATED (US) 1985-12-24 US disclosed
US-4556667-A (2-((AMINOPYRIDINYL)AMINO)PHENYL)ARYLMETHANONE INTERMEDIATES A. H. ROBINS COMPANY, INCORPORATED (US) 1985-12-03 US disclosed
EP-0157656-A2 Process and intermediates for the preparation of aryl substituded pyrido [1,4] benzodiazepines A.H. ROBINS COMPANY, INCORPORATED (US) 1985-10-09 EP disclosed
US-4495183-A ANTIULCER AGENTS- GASTROLINTESTINAL DISORDERS A. H. ROBINS COMPANY, INCORPORATED (US) 1985-01-22 US disclosed
US-4447361-A ANTIDEPRESSANT A. H. ROBINS COMPANY, INC. (US) 1984-05-08 US disclosed
EP-0076017-A2 Phenyl substituted pyrido(1,4)benzodiazepines and intermediates therefor A.H. ROBINS COMPANY, INCORPORATED (US) 1983-04-06 EP disclosed