SCHEMBL3222585

SCHEMBL3222585

COc1ccc(-c2nc(-c3ccc(C)cc3C)nc(-c3ccc(C)cc3C)n2)c(O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.60
MEN1 O00255 9/20 0.47
KMT2A Q03164 9/20 0.47
RAB9A P51151 3/20 0.47
CASP3 P42574 2/20 0.47
SENP8 Q96LD8 2/20 0.47
SENP7 Q9BQF6 2/20 0.47
SENP6 Q9GZR1 2/20 0.47
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
NOTUM Q6P988 1/20 0.44
IDH1 O75874 1/20 0.43
MAPT P10636 5/20 0.42
LMNA P02545 3/20 0.42
TSHR P16473 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
KDM4E B2RXH2 2/20 0.41
ALOX12 P18054 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30056432 1.00 NPC1 (0.60) NPC1MEN1KMT2ARAB9ACASP3
SCHEMBL19756253 0.92 NPC1 (0.66) NPC1MEN1KMT2ARAB9ACASP3
SCHEMBL29236319 0.91 NPC1 (0.51) NPC1MEN1KMT2ARAB9ACASP3
SCHEMBL19756248 0.88 NPC1 (0.60) NPC1MEN1KMT2ARAB9ACASP3
SCHEMBL13030444 0.87 NPC1 (0.77) NPC1MEN1KMT2ARAB9AMGAM
SCHEMBL19756249 0.86 NPC1 (0.59) NPC1MEN1KMT2ARAB9ACASP3
SCHEMBL12996861 0.85 NPC1 (0.46) NPC1MEN1KMT2ARAB9ACASP3
SCHEMBL15070194 0.85 NPC1 (0.57) NPC1MEN1KMT2ARAB9ACASP3
SCHEMBL19756254 0.85 NPC1 (0.57) NPC1MEN1KMT2ARAB9ACASP3
SCHEMBL9917147 0.85 NPC1 (0.57) NPC1MEN1KMT2ARAB9AMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250011590-A1 OPTICAL FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2025-01-09 US disclosed
EP-4431989-A1 OPTICAL FILM AND POLARIZING PLATE Tosoh Corporation (JP) 2024-09-18 EP disclosed
WO-2023090353-A1 OPTICAL FILM AND POLARIZING PLATE 東ソー株式会社 2023-05-25 WO disclosed
CN-109651275-B Triazine compound, composition and preparation method thereof 江苏裕事达新材料科技有限责任公司 2022-12-06 CN disclosed
US-20220144712-A1 SHAPED ARTIFICIAL POLYMER ARTICLES BASF SE (DE) 2022-05-12 US disclosed
US-20210095096-A1 PROTECTIVE FILM AND SHEET TOPPAN PRINTING CO.,LTD. (JP) 2021-04-01 US disclosed
EP-3137296-B1 MULTI-LAYERED FILM AND THE USE THEREOF BASF SE (DE) 2018-08-01 EP disclosed
US-9732254-B2 Multi-layered film and the use thereof BASF SE (DE) 2017-08-15 US disclosed
US-20170058151-A1 MULTI-LAYERED FILM AND THE USE THEREOF BASF SE (DE) 2017-03-02 US disclosed
US-9193838-B2 High concentration pelletized additive concentrates for polymer INGENIA POLYMERS, INC. (US) 2015-11-24 US disclosed
US-20070073007-A1 Polyacetal resin composition and molded article thereof POLYPLASTICS CO., LTD. (JP) 2007-03-29 US disclosed
EP-1522554-B1 Polyacetal resin composition and shaped article thereof POLYPLASTICS CO (JP) 2006-11-22 EP disclosed
EP-1688461-A1 POLYACETAL RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Polyplastics Co., Ltd. (JP) 2006-08-09 EP disclosed
EP-1522554-A1 Polyacetal resin composition and shaped article thereof Polyplastics Co., Ltd. (JP) 2005-04-13 EP disclosed
EP-0500496-B2 Stabilised polymers containing heteroatoms in the main chain CIBA SC HOLDING AG (CH) 2002-01-30 EP disclosed
EP-0500496-B1 Stabilised polymers containing heteroatoms in the main chain CIBA GEIGY AG (CH) 1997-08-27 EP disclosed
US-5288778-A Containing hydroxyphenyltriazine CIBA-GEIGY CORPORATION (US) 1994-02-22 US disclosed
EP-0500496-A1 Stabilised polymers containing heteroatoms in the main chain CIBA-GEIGY AG (CH) 1992-08-26 EP disclosed
US-4964871-A Process for preventing yellowing of polyamide fibre materials treated with stain-blocking agents by treatment with water-soluble light stabilizer having fibre affinity CIBA-GEIGY CORPORATION (US) 1990-10-23 US disclosed
EP-0345212-A1 Process to prevent yellowing of polyamide fibres finished with stain-proofing agents CIBA-GEIGY AG (CH) 1989-12-06 EP disclosed