Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 17/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 17/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3223028 | 0.84 | PDGFRB (0.43) | PDGFRBPDGFRAAXLCHEK2CHEK1 | |
| SCHEMBL3219234 | 0.71 | PDGFRB (0.51) | PDGFRBPDGFRAAXLCHEK2CHEK1 | |
| SCHEMBL3227874 | 0.66 | AAK1 (0.31) | — | |
| SCHEMBL3730948 | 0.66 | PDGFRB (0.30) | PDGFRBPDGFRA | |
| SCHEMBL8501272 | 0.65 | PDGFRB (1.00) | PDGFRBPDGFRA | |
| SCHEMBL3728623 | 0.65 | — | — | |
| SCHEMBL8172666 | 0.64 | PDGFRB (1.00) | PDGFRBPDGFRA | |
| SCHEMBL3738957 | 0.64 | PDGFRB (0.32) | PDGFRBPDGFRA | |
| SCHEMBL3217590 | 0.63 | PDGFRB (0.35) | PDGFRBPDGFRA | |
| SCHEMBL3728288 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056570-A1 | FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| EP-2068632-A1 | FUNGICIDES | Syngeta Participations AG (CH) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008028624-A1 | FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056570-A1 | FUNGICIDES | CYP21A2, CYP51A1, CYP4X1 | PDGFRB 4516/4885PDGFRA 4427/4885AXL 1989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.