Benzene

Benzene

SCHEMBL3223041

CCCc1ccccc1.c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.58
ALDH1A1 P00352 2/20 0.55
HPGD P15428 1/20 0.55
ALOX15 P16050 1/20 0.55
ALOX12 P18054 1/20 0.55
CASP1 P29466 1/20 0.55
HSD17B10 Q99714 1/20 0.55
TAAR1 Q96RJ0 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
CYP2A6 P11509 1/20 0.52
HTR2A P28223 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
LOXL2 Q9Y4K0 1/20 0.52
ATM Q13315 1/20 0.52
SIGMAR1 Q99720 3/20 0.52
AOC3 Q16853 2/20 0.50
CHRM2 P08172 1/20 0.50
HTR1A P08908 1/20 0.50
ADRA2A P08913 1/20 0.50
CHRM1 P11229 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40575 1.00
Benzene SCHEMBL28308118 1.00 TP53 (0.58) TP53ALDH1A1HPGDALOX15ALOX12
SCHEMBL11594885 1.00 TP53 (0.58) TP53ALDH1A1HPGDALOX15ALOX12
SCHEMBL31498535 0.97 TP53 (0.55) TP53ALDH1A1HPGDALOX15ALOX12
Hydrochloric Acid SCHEMBL5792976 0.97 TP53 (0.55) TP53ALDH1A1HPGDALOX15ALOX12
SCHEMBL9420959 0.97 TP53 (0.55) TP53ALDH1A1HPGDALOX15ALOX12
Bromide SCHEMBL7216374 0.97 TP53 (0.55) TP53ALDH1A1HPGDALOX15ALOX12
Ammonia Solution, Strong SCHEMBL479482 0.97 TP53 (0.55) TP53ALDH1A1HPGDALOX15ALOX12
Iodide SCHEMBL10910035 0.97 TP53 (0.55) TP53ALDH1A1HPGDALOX15ALOX12
Iodide SCHEMBL28827008 0.97 TP53 (0.55) TP53ALDH1A1HPGDALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110054541-B Preparation method of deuterated aromatic compound 安徽秀朗新材料科技有限公司 2022-05-27 CN disclosed
CN-110054541-A A kind of preparation method of deuterated aromatic compound 安徽秀朗新材料科技有限公司 2019-07-26 CN disclosed
CN-109478595-A Organic Thin Film Transistors, organic semiconductor film, compound, Organic Thin Film Transistors composition and Organic Thin Film Transistors manufacturing method 富士胶片株式会社 2019-03-15 CN disclosed
CN-107001929-A Electronic device 默克专利有限公司 2017-08-01 CN disclosed
WO-2010021772-A1 ALKYLATION SLURRY REACTOR CATALYTIC DISTILLATION TECHNOLOGIES (US) 2010-02-25 WO disclosed
WO-2010021773-A2 REFORMATE BENZENE REDUCTION VIA ALKYLATION CATALYTIC DISTILLATION TECNOLOGIES (US) 2010-02-25 WO disclosed
CN-101287690-A A method of making aromatic products SHELL INT RESEARCH (NL) 2008-10-15 CN disclosed