SCHEMBL3223372

SCHEMBL3223372

CCCCc1ccc2ccccc2c1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 5/20 0.50
MCL1 Q07820 5/20 0.50
BCL2L1 Q07817 4/20 0.50
BAK1 Q16611 4/20 0.50
PPARA Q07869 3/20 0.50
KAT8 Q9H7Z6 2/20 0.50
PPARG P37231 2/20 0.50
EP300 Q09472 1/20 0.50
KAT2A Q92830 1/20 0.50
KAT2B Q92831 1/20 0.50
KAT5 Q92993 1/20 0.50
SAE1 Q9UBE0 1/20 0.50
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP1A2 P05177 1/20 0.47
GLA P06280 1/20 0.47
HPGD P15428 1/20 0.47
CYP2C19 P33261 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL7713405 0.98 BID (0.49) BIDMCL1BCL2L1BAK1PPARA
Ammonia Solution, Strong SCHEMBL7713404 0.98 BID (0.49) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL9256709 0.95 BID (0.56) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL11342368 0.94 BID (0.58) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL7184885 0.94 BID (0.58) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL10422649 0.94 BID (0.58) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL5709971 0.94 BID (0.58) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL5575883 0.94 BID (0.58) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL8665018 0.94 BID (0.58) BIDMCL1BCL2L1BAK1PPARA
Ammonia Solution, Strong SCHEMBL4296360 0.93 BID (0.57) BIDMCL1BCL2L1BAK1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8399168-B2 Method for producing toner, two-component developer, developing device and image forming apparatus SHARP KABUSHIKI KAISHA (JP) 2013-03-19 US disclosed
US-20120316337-A1 METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP UNIVERSITE DU MAINE (FR) 2012-12-13 US disclosed
CN-101560272-B Olefinic polymerization catalyst, preparation method and polymerization method YINGKOU XIANGYANG CATALYST CO LTD 2011-04-13 CN disclosed
CN-101560273-B Olefinic polymerization catalyst, preparation method and polymerization method YINGKOU XIANGYANG CATALYST CO LTD 2011-03-23 CN disclosed
US-20100055597-A1 METHOD FOR PRODUCING TONER, TWO-COMPONENT DEVELOPER, DEVELOPING DEVICE AND IMAGE FORMING APPARATUS SHARP KABUSHIKI KAISHA (JP) 2010-03-04 US disclosed
CN-101560273-A Olefinic polymerization catalyst, preparation method and polymerization method YINGKOU XIANGYANG CATALYST CO (CN) 2009-10-21 CN disclosed
CN-101560272-A Olefinic polymerization catalyst, preparation method and polymerization method YINGKOU XIANGYANG CATALYST CO (CN) 2009-10-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120316337-A1 METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP COMT, NAA15, NUDC BID 2799/4885MCL1 1600/4885BCL2L1 4097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.