⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73036 | 0.78 | — | — | |
| SCHEMBL9935005 | 0.73 | — | — | |
| SCHEMBL1351735 | 0.70 | — | — | |
| SCHEMBL2438093 | 0.67 | — | — | |
| SCHEMBL24819202 | 0.66 | — | — | |
| SCHEMBL2968795 | 0.66 | — | — | |
| SCHEMBL30218035 | 0.66 | HTR2A (0.35) | — | |
| SCHEMBL22516834 | 0.66 | — | — | |
| SCHEMBL14428593 | 0.66 | — | — | |
| Propiolactone SCHEMBL28204521 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713312-B2 | Substituted bicyclic compounds as farnesoid X receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-08-01 | — | — | US | claimed |
| US-20230192690-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | PFIZER (US) | 2023-06-22 | — | — | US | claimed |
| US-20230117470-A1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS TOLL RECEPTOR INHIBITORS | SYNGENE INTERNATIONAL LIMITED (IN) | 2023-04-20 | — | — | US | claimed |
| CN-114929345-A | Substituted pyrazole compounds as TOLL receptor inhibitors | 百时美施贵宝公司 | 2022-08-19 | — | — | CN | claimed |
| CN-110944998-B | Dihydro-pyrrolo-pyridine derivatives | 辉瑞大药厂 | 2022-08-16 | — | — | CN | claimed |
| CN-114761404-A | Substituted bicyclic heteroaryl compounds | 百时美施贵宝公司 | 2022-07-15 | — | — | CN | claimed |
| US-20220135550-A1 | SUBSTITUTED BICYCLIC COMPOUNDS AS FARNESOID X RECEPTOR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2022-05-05 | — | — | US | claimed |
| CN-109641898-B | 5, 7-dihydro-pyrrolo-pyridine derivatives for the treatment of neurological and neurodegenerative diseases | 辉瑞公司 | 2022-04-08 | — | — | CN | claimed |
| CN-109415345-B | Pyridazinone-based broad-spectrum anti-influenza inhibitors | 豪夫迈·罗氏有限公司 | 2022-01-11 | — | — | CN | claimed |
| EP-3924336-A1 | SUBSTITUTED BICYCLIC COMPOUNDS AS FARNESOID X RECEPTOR MODULATORS | Bristol-Myers Squibb Company (US) | 2021-12-22 | — | — | EP | claimed |
| CN-103380122-A | Novel benzodioxole piperazine compounds | HOFFMANN LA ROCHE | 2013-10-30 | — | — | CN | claimed |
| EP-2638029-A1 | TRIAZOLE DERIVATIVES AND THEIR USE FOR NEUROLOGICAL DISORDERS | F.HOFFMANN-LA ROCHE AG (CH) | 2013-09-18 | — | — | EP | claimed |
| WO-2013127269-A1 | AMIDO SPIROCYCLIC AMIDE AND SULFONAMIDE DERIVATIVES | GENENTECH,INC. (US) | 2013-09-06 | — | — | WO | claimed |
| CN-103221402-A | Triazole derivatives and their use for neurological disorders | HOFFMANN LA ROCHE | 2013-07-24 | — | — | CN | claimed |
| US-20130040948-A1 | NOVEL BENZODIOXOLE PIPERAZINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-02-14 | — | — | US | claimed |
| WO-2012110470-A1 | NOVEL BENZODIOXOLE PIPERAZINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-08-23 | — | — | WO | claimed |
| WO-2012062687-A1 | TRIAZOLE DERIVATIVES AND THEIR USE FOR NEUROLOGICAL DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-05-18 | — | — | WO | claimed |
| US-20120115844-A1 | NOVEL TRIAZOLE COMPOUNDS I | ROCHE PALO ALTO LLC | 2012-05-10 | — | — | US | claimed |
| EP-2214624-A2 | STYLING AGENT | Henkel AG & Co. KGaA (DE) | 2010-08-11 | — | — | EP | claimed |
| WO-2009071416-A2 | STYLING AGENT | HENKEL AG & CO. KGAA (DE) | 2009-06-11 | — | — | WO | claimed |