Dl-Tryptophan

Dl-Tryptophan

SCHEMBL3225365

NC(CO)C(=O)O.NC(Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.89
▸ KDM4E B2RXH2 3/20 0.89
▸ MAPT P10636 3/20 0.89
▸ LMNA P02545 2/20 0.89
▸ TSHR P16473 2/20 0.89
▸ BLM P54132 2/20 0.89
▸ PMP22 Q01453 2/20 0.89
▸ MEN1 O00255 2/20 0.89
▸ MPO P05164 1/20 0.89
▸ HIF1A Q16665 1/20 0.89
▸ SMN1; SMN2 Q16637 1/20 0.63
▸ APAF1 O14727 1/20 0.62
▸ POLB P06746 1/20 0.62
▸ RECQL P46063 1/20 0.62
▸ L3MBTL1 Q9Y468 1/20 0.62
▸ HTR2A P28223 3/20 0.61
▸ HTR1A P08908 2/20 0.61
▸ HTR2C P28335 2/20 0.61
▸ SLC6A4 P31645 2/20 0.61
▸ HTR7 P34969 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tryptophan SCHEMBL3225377 1.00 KMT2A (0.89) KMT2AKDM4EMAPTLMNATSHR
Dl-Tryptophan SCHEMBL27533141 1.00 KMT2A (0.89) KMT2AKDM4EMAPTLMNATSHR
Dl-Tryptophan SCHEMBL27147332 1.00 KMT2A (0.89) KMT2AKDM4EMAPTLMNATSHR
Tryptophan SCHEMBL7103661 0.95 KDM4E (0.80) KMT2AKDM4EMAPTLMNATSHR
Tryptophan SCHEMBL23141133 0.94 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR
Dl-Tryptophan SCHEMBL4732052 0.94 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR
Tryptophan SCHEMBL475350 0.94 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR
Dl-Tryptophan SCHEMBL7327 0.94 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR
Dl-Tryptophan SCHEMBL475349 0.94 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR
Dl-Tryptophan SCHEMBL19161120 0.94 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4073687-A PENICILLINS OR CEPHALOSPORINS SHIONOGI & CO., LTD. (JA) 1978-02-14 — — US claimed
EP-4149493-A1 METHOD OF TREATMENT OF CANCER OR TUMOUR Adaptimmune Limited (GB) 2023-03-22 — — EP disclosed
EP-4149492-A1 MODIFIED IPSCS Adaptimmune Limited (GB) 2023-03-22 — — EP disclosed
EP-4149631-A1 METHOD OF TREATMENT OF CANCER OR TUMOUR Adaptimmune Limited (GB) 2023-03-22 — — EP disclosed
CN-115233470-A Preparation method of anti-mite silk fabric based on bergamot pigment 达利(中国)有限公司 2022-10-25 — — CN disclosed
WO-2021229235-A1 METHOD OF TREATMENT OF CANCER OR TUMOUR ADAPTIMMUNE LIMITED (GB) 2021-11-18 — — WO disclosed
WO-2021229234-A1 METHOD OF TREATMENT OF CANCER OR TUMOUR ADAPTIMMUNE LIMITED (GB) 2021-11-18 — — WO disclosed
WO-2021229212-A1 MODIFIED IPSCS ADAPTIMMUNE LIMITED (GB) 2021-11-18 — — WO disclosed
CN-106148311-B A kind of mutant of D-Psicose -3- epimerase and its application 上海立足生物科技有限公司 2019-06-21 — — CN disclosed
CN-108392667-A Desalination scar medical dressing with tissue inducing function and preparation method thereof 苏州纳晶医药技术有限公司 2018-08-14 — — CN disclosed
CN-101906429-A Serine-tryptophan protein kinase gene and preparation method and application thereof UNIV WUHAN 2010-12-08 — — CN disclosed
US-20100065493-A1 MICROBIAL DEGRADATION OF WATER-BORNE PAINT CONTAINING HIGH LEVELS OF ORGANIC SOLVENT ATOTECH DEUTSCHLAND GMBH & CO. KG (F/K/A ATOTECH DEUTSCHLAND GMBH) (DE) 2010-03-18 — — US disclosed
EP-2111378-A2 MICROBIAL DEGRADATION OF WATER-BORNE PAINT CONTAINING HIGH LEVELS OF ORGANIC SOLVENT ATOTECH Deutschland GmbH (DE) 2009-10-28 — — EP disclosed
US-20090023188-A1 Heparin/heparosan synthase from P. multocida and methods of making and using same NATIONAL SCIENCE FOUNDATION 2009-01-22 — — US disclosed
WO-2008094872-A2 MICROBIAL DEGRADATION OF WATER-BORNE PAINT CONTAINING HIGH LEVELS OF ORGANIC SOLVENT ATOTECH DEUTSCHLAND GMBH (DE) 2008-08-07 — — WO disclosed
US-20080185337-A1 MICROBIAL DEGRADATION OF WATER-BORNE PAINT CONTAINING HIGH LEVELS OF ORGANIC SOLVENT ATOTECH DEUTSCHLAND GMBH (DE) 2008-08-07 — — US disclosed
CN-1976595-A Preparation of canola protein isolate and use in aquaculture BURCON NUTRASCIENCE (CA) 2007-06-06 — — CN disclosed
US-6362275-B1 MIXTURE CONTAINING AMINO ACID ASHLAND INC. 2002-03-26 — — US disclosed
EP-0498665-B1 Hydroxamic acids derivatives, process for their preparation and use thereof BRITISH BIOTECH PHARM (GB) 1996-04-24 — — EP disclosed
US-4801529-A INCUBATION, SEPARATION, DETECTION; ENZYMES, ANTIGENS, ANTIBODIES BRANDEIS UNIVERSITY (US) 1989-01-31 — — US disclosed
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