Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 2/20 | 0.50 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.48 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3233383 | 0.95 | CSNK1D (0.49) | ROCK1CSNK1DNTRK1NTRK2MAPT | |
| SCHEMBL3233452 | 0.94 | ROCK1 (0.49) | ROCK1CSNK1DNTRK1NTRK2MAPT | |
| SCHEMBL3232644 | 0.93 | PLA2G4B (0.50) | ROCK1CSNK1DNTRK1NTRK2MAPT | |
| SCHEMBL3235893 | 0.92 | CSNK1D (0.56) | ROCK1CSNK1DNTRK1NTRK2MAPT | |
| SCHEMBL3237423 | 0.91 | ROCK1 (0.48) | ROCK1CSNK1DNTRK1NTRK2MAPT | |
| SCHEMBL3232502 | 0.91 | ROCK1 (0.49) | ROCK1CSNK1DNTRK1NTRK2MAPT | |
| SCHEMBL3229341 | 0.91 | ROCK1 (0.46) | ROCK1CSNK1DCTPS1NTRK1NTRK2 | |
| SCHEMBL3229388 | 0.90 | ROCK1 (0.47) | ROCK1CSNK1DNTRK1NTRK2MAPT | |
| SCHEMBL3235944 | 0.90 | ROCK1 (0.47) | ROCK1CSNK1DNTRK1NTRK2MAPT | |
| SCHEMBL3237711 | 0.90 | ROCK1 (0.49) | ROCK1CSNK1DNTRK1NTRK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024365-A1 | AMIDE COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-04 | — | — | WO | claimed |
| WO-2010024365-A1 | AMIDE COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-04 | — | — | WO | disclosed |
| WO-2010024365-A1 | AMIDE COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-04 | — | — | WO | disclosed |