Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 19/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 19/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226760 | 1.00 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL3220067 | 0.77 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3220074 | 0.77 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL128076 | 0.76 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL128075 | 0.76 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL247446 | 0.74 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4D | |
| Benzene SCHEMBL28266121 | 0.74 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10960854 | 0.72 | AKR1C3 (0.50) | PDE4APDE4DKMT2A | |
| SCHEMBL27684141 | 0.71 | PDE4A (0.79) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24704152 | 0.70 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012812-A1 | BENZAZEPINES AND BENZAZOCINES AS SIGMA-RECEPTOR LIGANDES | Westfälische Wilhelms Universität Münster (DE) | 2010-02-04 | — | — | WO | disclosed |