SCHEMBL3227580

SCHEMBL3227580

O=COn1c(=O)ccc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.50
CA9 Q16790 2/20 0.50
BRD4 O60885 1/20 0.50
BRPF1 P55201 1/20 0.50
KAT2B Q92831 1/20 0.50
BRD9 Q9H8M2 1/20 0.50
KMT2A Q03164 3/20 0.37
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 3/20 0.33
PRKD3 O94806 1/20 0.33
PRKCG P05129 1/20 0.33
PRKCB P05771 1/20 0.33
PRKCA P17252 1/20 0.33
PRKACA P17612 1/20 0.33
PRKACG P22612 1/20 0.33
PRKACB P22694 1/20 0.33
PRKCH P24723 1/20 0.33
PRKCI P41743 1/20 0.33
PRKCE Q02156 1/20 0.33
PRKCQ Q04759 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10661265 0.82 CA12 (0.55) CA12CA9BRD4BRPF1KAT2B
SCHEMBL11408836 0.80 CA12 (0.50) CA12CA9BRD4BRPF1KAT2B
SCHEMBL9408040 0.80 CA12 (0.50) CA12CA9BRD4BRPF1KAT2B
SCHEMBL1050540 0.78 CA12 (0.57) CA12CA9BRD4BRPF1KAT2B
SCHEMBL14763348 0.76 CA12 (0.48) CA12CA9BRD4BRPF1KAT2B
SCHEMBL4424854 0.76 CA12 (0.48) CA12CA9BRD4BRPF1KAT2B
SCHEMBL10326300 0.75 CA12 (0.44) CA12CA9BRD4BRPF1KAT2B
SCHEMBL1972478 0.75 CA12 (0.44) CA12CA9BRD4BRPF1KAT2B
SCHEMBL16896766 0.74 CA12 (0.47) CA12CA9BRD4BRPF1KAT2B
SCHEMBL31324227 0.74 CA12 (0.47) CA12CA9BRD4BRPF1KAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102584819-B Salt of carbostyril formic acid compound as well as preparation method and application of salt NANJING YOKO BIO PHARMA RES CO LTD 2014-05-14 CN disclosed
CN-102584819-A Salt of carbostyril formic acid compound as well as preparation method and application of salt NANJING YOKO BIO PHARMA RES CO LTD 2012-07-18 CN disclosed
WO-2010015792-A1 NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS BIFUNCTIONAL MODULATORS OF M3 RECEPTORS AND BETA-2 RECEPTORS ARGENTA DISCOVERY LIMITED (GB) 2010-02-11 WO disclosed