⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3228177 | 1.00 | — | — | |
| SCHEMBL6559471 | 1.00 | — | — | |
| SCHEMBL2692497 | 1.00 | — | — | |
| SCHEMBL2693338 | 1.00 | — | — | |
| SCHEMBL2034245 | 1.00 | — | — | |
| SCHEMBL5897097 | 1.00 | — | — | |
| SCHEMBL5897084 | 1.00 | — | — | |
| Water SCHEMBL16700845 | 0.97 | PEPD (0.45) | — | |
| SCHEMBL3339166 | 0.94 | MEN1 (0.43) | — | |
| SCHEMBL5897163 | 0.94 | MEN1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101892-A1 | POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS AND USES THEREOF | Astellas Engineered Small Molecules US, Incorporated (US) | 2025-05-15 | — | — | WO | disclosed |
| EP-3418282-A1 | TRICYCLIC COMPOUND SERVING AS IMMUNOMODULATOR | Chai Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2018-12-26 | — | — | EP | disclosed |
| WO-2010015588-A1 | BENZYL-SUBSTITUTED TETRACYCLIC HETEROCYCLIC COMPOUNDS | NYCOMED GMBH (DE) | 2010-02-11 | — | — | WO | disclosed |
| US-7358250-B2 | Pyrrolo[2,3-d]pyrimidines that modulate ACK1 activity | AMGEN INC. (US) | 2008-04-15 | — | — | US | disclosed |
| US-20060040965-A1 | Pyrrolo[2,3-d]pyrimidines that modulate ACK1 activity | AMGEN INC. | 2006-02-23 | — | — | US | disclosed |