SCHEMBL3228440

SCHEMBL3228440

CC(C)C(NC(=O)c1cc(-c2ccc(NC(=O)Nc3ccccc3F)cc2)no1)C(=O)O.COC(=O)C(NC(=O)c1cc(-c2ccc(NC(=O)Nc3ccccc3F)cc2)no1)C(C)C

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CSGALNACT1 Q8TDX6 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2294252 0.97 CSGALNACT1 (0.68) CSGALNACT1
SCHEMBL2294246 0.97 CSGALNACT1 (0.68) CSGALNACT1
SCHEMBL3237048 0.95 CSGALNACT1 (0.67) CSGALNACT1
SCHEMBL2298940 0.95 CSGALNACT1 (0.82) CSGALNACT1
SCHEMBL2297151 0.95 CSGALNACT1 (0.82) CSGALNACT1
SCHEMBL2299208 0.89 CSGALNACT1 (0.62) CSGALNACT1
SCHEMBL2298633 0.89 CSGALNACT1 (0.74) CSGALNACT1
SCHEMBL2298643 0.89 CSGALNACT1 (0.74) CSGALNACT1
SCHEMBL2297158 0.88 CSGALNACT1 (0.65) CSGALNACT1
SCHEMBL2297159 0.88 CSGALNACT1 (0.65) CSGALNACT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010023609-A1 OXAZOLE, OXADIAZOLE AND THIAZOLE DERIVATIVES AS DIACYLGLYCEROL ACYLTRANFERASE INHIBITORS PIRAMAL LIFE SCIENCES LIMITED (IN) 2010-03-04 WO disclosed