SCHEMBL322990

SCHEMBL322990

Cc1ccc(S(=O)(=O)Nc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 1.00
CA9 Q16790 2/20 1.00
CA1 P00915 1/20 1.00
CA2 P00918 1/20 1.00
KMT2A Q03164 4/20 0.86
MEN1 O00255 3/20 0.86
GAA P10253 2/20 0.86
ALDH1A1 P00352 7/20 0.74
PKM P14618 1/20 0.74
KEAP1 Q14145 2/20 0.73
IL1RN P18510 1/20 0.73
ERAP1 Q9NZ08 1/20 0.73
FFAR1 O14842 1/20 0.73
ALOX12 P18054 2/20 0.68
GFER P55789 2/20 0.68
TDP1 Q9NUW8 2/20 0.68
CYP2C9 P11712 2/20 0.68
CYP2C19 P33261 2/20 0.68
HPGD P15428 2/20 0.68
KDM4E B2RXH2 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19119164 1.00 CA12 (1.00) CA12CA9CA1CA2KMT2A
SCHEMBL27824001 0.98 CA12 (0.96) CA12CA9CA1CA2KMT2A
Water SCHEMBL3944291 0.98 CA12 (0.96) CA12CA9CA1CA2KMT2A
SCHEMBL28689444 0.98 CA12 (0.96) CA12CA9CA1CA2KMT2A
SCHEMBL13167620 0.94 CA12 (0.89) CA12CA9CA1CA2KMT2A
SCHEMBL9479370 0.93 KMT2A (1.00) CA12CA9CA1CA2KMT2A
SCHEMBL1952693 0.93 KMT2A (1.00) CA12CA9CA1CA2KMT2A
SCHEMBL92717 0.93 KMT2A (1.00) CA12CA9CA1CA2KMT2A
SCHEMBL806766 0.92 CA12 (0.85) CA12CA9CA1CA2KMT2A
Ammonia Solution, Strong SCHEMBL15741206 0.91 KMT2A (0.97) CA12CA9CA1CA2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 819 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111393304-B Method for preparing p-phenylenediamine from aniline 江苏扬农化工集团有限公司 2023-01-17 CN claimed
CN-110526832-B Method for preparing polysubstituted alicyclic compound 浙江师范大学 2022-06-10 CN claimed
CN-114075151-A 3,4-2H-1, 3-oxazine-2-ketone compounds and preparation method thereof 复旦大学 2022-02-22 CN claimed
CN-111393304-A Method for preparing p-phenylenediamine from aniline 江苏扬农化工集团有限公司 2020-07-10 CN claimed
EP-2998359-B1 METHOD FOR IMPROVING THE ELECTRICAL-INSULATING PROPERTY AND THE FOGGING RESISTANCE OF A POLYESTER RESIN COMPOSITION ADEKA CORP (JP) 2019-08-21 EP claimed
EP-3075784-B1 PROCESS FOR PRODUCING MASTERBATCH ADEKA CORP (JP) 2018-10-03 EP claimed
EP-2484725-B1 POLYESTER RESIN COMPOSITION, POLYESTER FIBER, POLYESTER RESIN MOLDED ARTICLE, AND PROCESS FOR PRODUCTION OF NUCLEATING AGENT FOR POLYESTER RESIN ADEKA CORP (JP) 2017-07-19 EP claimed
EP-2934142-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO Dow AgroSciences LLC (US) 2015-10-28 EP claimed
WO-2014120355-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2014-08-07 WO claimed
US-20140001672-A1 POLYESTER RESIN COMPOSITION, POLYESTER FIBER, POLYESTER RESIN MOLDED ARTICLE, AND PROCESS FOR PRODUCTION OF NUCLEATING AGENT FOR POLYESTER RESIN ADEKA CORPORATION (JP) 2014-01-02 US claimed
US-20110313000-A1 CCR9 INHIBITORS AND METHODS OF USE THEREOF MILLENNIUM PHARMACEUTICALS, INC. (US) 2011-12-22 US claimed
US-20100280074-A1 CCR9 INHIBITORS AND METHODS OF USE THEREOF MILLENNIUM PHARMACEUTICALS, INC. (US) 2010-11-04 US claimed
US-20090054495-A1 CCR9 inhibitors and methods of use thereof MILLENNIUM PHARMACEUTICALS, INC. 2009-02-26 US claimed
US-20080078293-A1 REMOVING METHOD AND APPARATUS FOR HIGH-MELTING POINT COMPOUND, SOLVENT RECOVERING METHOD AND SOLVENT RECOVERING APPARATUS FUJIFILM CORPORATION (JP) 2008-04-03 US claimed
US-20060238684-A1 Liquid crystal panel and liquid crystal display apparatus NITTO DENKO CORPORATION (JP) 2006-10-26 US claimed
US-6335306-B1 SUBBING LAYER OF COLOR DEVELOPABILITY REDUCING AGENT AND IMAGE-FORMING LAYER OF COLORLESS OR LIGHT-COLORED DYE PRECURSOR AND COLOR-DEVELOPER; HEATED AND FIXED AT HIGH TEMPERATURE, IMAGE HAS HIGH SOLVENT RESISTANCE, IMAGE CLARITY OJI PAPER CO., LTD. (JP) 2002-01-01 US claimed
US-5256493-A Crosslinking agent for heat curable coatings CYTEC TECHNOLOGY CORP. 1993-10-26 US claimed
US-4968737-A Molding compounds comprising a thermoplastically processible aromatic polyamide HUELS AKTIENGESELLSCHAFT (DE) 1990-11-06 US claimed
US-4929530-A OXIDATIVE LEUCO DYES, PHOTO-OXIDIZERS, REDUCING AGENTS, ORGANIC SULFONAMIDES AND PHENOLIC COMPONENTS; EXPOSING TO LIGHT FUJI PHOTO FILM CO., LTD. (JP) 1990-05-29 US claimed
EP-0349204-A2 Use and regeneration of reagents using coupled reactions and permselective barriers BEND RESEARCH, INC. (US) 1990-01-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110313000-A1 CCR9 INHIBITORS AND METHODS OF USE THEREOF CCR9, CCR1, CCR4 CA12 1413/4885CA9 85/4885CA1 1331/4885
US-20100280074-A1 CCR9 INHIBITORS AND METHODS OF USE THEREOF CCR9, CCR1, CCR4 CA12 1413/4885CA9 85/4885CA1 1331/4885
US-20090054495-A1 CCR9 inhibitors and methods of use thereof CCR9, CCR1, CCR4 CA12 1413/4885CA9 85/4885CA1 1331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.