SCHEMBL3230336

SCHEMBL3230336

NC(=O)NN1CSc2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BCHE P06276 5/20 0.43
ACHE P22303 2/20 0.43
NOTUM Q6P988 1/20 0.41
KDM4E B2RXH2 1/20 0.40
HSD17B3 P37058 1/20 0.39
LMNA P02545 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HPGD P15428 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
GAA P10253 1/20 0.37
GSK3B P49841 1/20 0.36
NOX1 Q9Y5S8 1/20 0.36
ALDH1A1 P00352 1/20 0.35
GFER P55789 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
SHMT2 P34897 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5524073 0.78 NOTUM (0.35) BCHEACHENOTUMKDM4EHSD17B3
SCHEMBL8176392 0.75 NOTUM (0.37) BCHEACHENOTUMKDM4EHSD17B3
SCHEMBL5026715 0.75 NOTUM (0.51) BCHEACHENOTUMKDM4EHSD17B3
SCHEMBL22585369 0.74 NOTUM (0.35) BCHEACHENOTUMKDM4EHSD17B3
SCHEMBL28877548 0.74 NOTUM (0.39) BCHEACHENOTUMKDM4EHSD17B3
SCHEMBL16095343 0.73 NOTUM (0.40) BCHEACHENOTUMKDM4EHSD17B3
SCHEMBL16095342 0.73 NOTUM (0.40) BCHEACHENOTUMKDM4EHSD17B3
SCHEMBL11193164 0.72 NOTUM (0.49) BCHEACHENOTUMKDM4EHSD17B3
SCHEMBL6935721 0.71 MAPT (0.43) BCHEACHENOTUMKDM4EHSD17B3
Bromide SCHEMBL2954210 0.70 MAPT (0.42) BCHEACHENOTUMKDM4EHSD17B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1308860-A Herbicide based on heteroaryloxyacetamides BAYER AG (DE) 2001-08-22 CN claimed
CN-1082815-A Herbicide based on heteroaryloxyacetamides BAYER AG (DE) 1994-03-02 CN claimed
EP-2236032-A2 Herbicidal agent on the basis of heteroaryloxyacetamides Bayer CropScience AG (DE) 2010-10-06 EP disclosed
EP-2236031-A2 Herbicidal agent on the basis of heteroaryloxyacetamides Bayer CropScience AG (DE) 2010-10-06 EP disclosed
EP-2213171-A2 Herbicidal agents based on heteroaryloxyacetamides Bayer CropScience AG (DE) 2010-08-04 EP disclosed
EP-2213170-A2 Herbicidal agents based on heteroaryloxyacetamides Bayer CropScience AG (DE) 2010-08-04 EP disclosed
EP-1623626-A2 Herbicidal agents based on heteroaryloxyacetamides Bayer CropScience AG (DE) 2006-02-08 EP disclosed
CN-1140175-C Herbicide based on heteroaryloxyacetamides 拜尔公司 2004-03-03 CN disclosed
CN-1081440-C Herbicidal compositions based on N-isopropyl -N -(4 -fluorophenyl) (5 -trifluoromethyl -1, 3, 4 -thiadiazol -2 -yloxy) acetamide BAYER AG (DE) 2002-03-27 CN disclosed
CN-1308860-A Herbicide based on heteroaryloxyacetamides BAYER AG (DE) 2001-08-22 CN disclosed
US-5985797-A SYNERGISTIC HERBICIDAL COMBINATIONS OF N-ISOPROPYL-N-(4-FLUOROPHENYL)(5-TRIFLUOROMETHYL-1,3,4-THIADIA ZOL-2-YLOXY) ACETAMIDE WITH FENOXAPROP-ETHYL AND/OR CLODINAFOP-PROPARGYL BAYER AKTIENGESELLSCHAFT (DE) 1999-11-16 US disclosed
US-5759955-A SYNERGISTIC MIXTURES WITH OTHER HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-06-02 US disclosed
CN-1179885-A Herbicidal compositions based on N-isopropyl -N -(4 -fluorophenyl) (5 -trifluoromethyl -1, 3, 4 -thiadiazol -2 -yloxy) acetamide BAYER AG (DE) 1998-04-29 CN disclosed
EP-0829202-A2 Herbicidal agents based on heteroaryloxyacetamides BAYER AG (DE) 1998-03-18 EP disclosed
US-5593942-A MIXTURES OF HERBICIDES WITH SYNERGISTIC COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1997-01-14 US disclosed
CN-1082815-A Herbicide based on heteroaryloxyacetamides BAYER AG (DE) 1994-03-02 CN disclosed