Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1975850 | 0.87 | CCR1 (0.53) | CCR1 | |
| SCHEMBL1975148 | 0.87 | CCR1 (0.53) | CCR1 | |
| SCHEMBL3671121 | 0.77 | CCR1 (0.37) | CCR1 | |
| SCHEMBL3333964 | 0.70 | CCR1 (0.47) | CCR1 | |
| SCHEMBL13737932 | 0.68 | CCR1 (0.53) | CCR1 | |
| SCHEMBL3332842 | 0.66 | MEN1 (0.37) | CCR1 | |
| SCHEMBL3332836 | 0.66 | MEN1 (0.37) | CCR1 | |
| SCHEMBL31284234 | 0.66 | NQO2 (0.34) | — | |
| SCHEMBL13739948 | 0.65 | CCR1 (0.48) | CCR1 | |
| SCHEMBL20838495 | 0.65 | CCR1 (0.44) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022081-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2010-02-25 | — | — | WO | disclosed |
| EP-2139888-A2 | IMIDAZOÝ1,2-A¨PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008121687-A2 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2008-10-09 | — | — | WO | disclosed |