Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | IDE | P14735 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1029523 | 0.85 | MAPT (0.38) | HTTMAPTITGB3ITGB2ITGB1 | |
| SCHEMBL10852667 | 0.84 | HTT (0.40) | HTTMAPTITGB3ITGB2ITGB1 | |
| SCHEMBL11241409 | 0.84 | HTT (0.40) | HTTMAPTITGB3ITGB2ITGB1 | |
| SCHEMBL10854263 | 0.84 | HTT (0.40) | HTTMAPTITGB3ITGB2ITGB1 | |
| SCHEMBL10853447 | 0.84 | HTT (0.40) | HTTMAPTITGB3ITGB2ITGB1 | |
| SCHEMBL10857021 | 0.84 | HTT (0.40) | HTTMAPTITGB3ITGB2ITGB1 | |
| SCHEMBL10857737 | 0.74 | HTT (0.33) | HTTMAPTITGB3ITGB2ITGB1 | |
| SCHEMBL10850753 | 0.74 | HTT (0.33) | HTTMAPTITGB3ITGB2ITGB1 | |
| SCHEMBL16421034 | 0.71 | ITGB1 (0.42) | HTTMAPTITGB3ITGB2ITGB1 | |
| SCHEMBL3759735 | 0.71 | EGFR (0.48) | MAPTTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010014909-A1 | IMMUNOMODULATORY PEPTIDES | SYNTONIX PHARMACEUTICALS, INC. (US) | 2010-02-04 | — | — | WO | disclosed |
| EP-1370276-A2 | MEDICAL USES OF INTERCELLULAR COMMUNICATION FACILITATING COMPOUNDS | Zealand Pharma A/S (DK) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002077017-A2 | MEDICAL USES OF INTERCELLULAR COMMUNICATION FACILITATING COMPOUNDS | ZEALAND PHARMA A/S (DK) | 2002-10-03 | — | — | WO | disclosed |