⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11917809 | 1.00 | — | — | |
| SCHEMBL13531791 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL27502631 | 0.97 | — | — | |
| Propane SCHEMBL11357480 | 0.92 | — | — | |
| SCHEMBL11345039 | 0.83 | SLC6A2 (0.32) | — | |
| SCHEMBL8945907 | 0.82 | — | — | |
| SCHEMBL10184347 | 0.80 | — | — | |
| SCHEMBL8217469 | 0.80 | — | — | |
| Tert-Butyl Formate SCHEMBL28312846 | 0.76 | TDP1 (0.46) | — | |
| Nitrous Acid SCHEMBL11793835 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024104425-A1 | KRAS INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 广东东阳光药业股份有限公司 | 2024-05-23 | — | — | WO | claimed |
| CN-118047801-A | KRAS inhibitor compound, pharmaceutical composition and application thereof | 广东东阳光药业股份有限公司 | 2024-05-17 | — | — | CN | claimed |
| US-20240140895-A1 | NOVEL AROMATIC MOLECULES | Xeniopro GmbH (DE) | 2024-05-02 | — | — | US | claimed |
| US-20230141913-A2 | PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY | Xeniopro GmbH (DE) | 2023-05-11 | — | — | US | claimed |
| CN-108026077-B | Phenoxymethyl derivatives | 豪夫迈·罗氏有限公司 | 2021-11-05 | — | — | CN | claimed |
| EP-3841095-A2 | AROMATIC MOLECULES FOR USE IN THE TREATMENT OF PATHOLOGICAL CONDITIONS | Xeniopro GmbH (DE) | 2021-06-30 | — | — | EP | claimed |
| EP-3841091-A1 | PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERATIVE ACTIVITY | Xeniopro GmbH (DE) | 2021-06-30 | — | — | EP | claimed |
| CN-112955439-A | Aromatic molecules for the treatment of pathological conditions | 赛尼欧普罗有限责任公司 | 2021-06-11 | — | — | CN | claimed |
| CN-112930337-A | Antiproliferative phenoxy (hetero) aryl ethers | 赛尼欧普罗有限责任公司 | 2021-06-08 | — | — | CN | claimed |
| WO-2020039094-A1 | PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERATIVE ACTIVITY | Xeniopro GmbH (DE) | 2020-02-27 | — | — | WO | claimed |
| WO-2005105777-A1 | SUBSTITUTED THIOPHENE AMIDE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-11-10 | — | — | WO | claimed |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| US-20040077641-A1 | Pyridyl pyrimidines for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2004-04-22 | — | — | US | claimed |
| EP-1367893-A1 | PYRIDYL PYRIMIDINES FOR USE AS PESTICIDES | Bayer CropScience AG (DE) | 2003-12-10 | — | — | EP | claimed |
| US-6465498-B2 | STABLE MICROBICIDAL FORMULATION, SOLUBILITY IN LIQUID PREPARATIONS | AIR LIQUIDE SANTE (INTERNATIONAL) (FR) | 2002-10-15 | — | — | US | claimed |
| WO-2002067684-A1 | PYRIDYL PYRIMIDINES FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2002-09-06 | — | — | WO | claimed |
| US-4757115-A | Reaction product of a polyisocyanate, a bicyclic amide acetal, and a hydroxy group-bearing free radically polymerizable ethylenically unsaturated monomer | ASHLAND OIL, INC. (US) | 1988-07-12 | — | — | US | claimed |
| EP-0064294-A1 | 1,5-Substituted isoquinoline derivatives | G.D. Searle & Co. (US) | 1982-11-10 | — | — | EP | claimed |
| US-4311827-A | Curable organosilicate coating compositions containing 1,3-oxazolidine curing agent | DESOTO, INC. (US) | 1982-01-19 | — | — | US | claimed |