Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13291842 | 0.97 | TRPV1 (0.36) | TRPV1DRD4DRD2HCRTR1HCRTR2 | |
| SCHEMBL13291811 | 0.96 | TRPV1 (0.37) | TRPV1DRD4DRD2HCRTR1HCRTR2 | |
| SCHEMBL13291810 | 0.96 | TRPV1 (0.39) | TRPV1DRD4DRD2HCRTR1HCRTR2 | |
| SCHEMBL13291839 | 0.95 | DRD4 (0.34) | TRPV1DRD4DRD2HCRTR1HCRTR2 | |
| SCHEMBL13291797 | 0.93 | TRPV1 (0.33) | TRPV1HCRTR2 | |
| SCHEMBL13291801 | 0.92 | TRPV1 (0.32) | TRPV1 | |
| SCHEMBL13291795 | 0.92 | TRPV1 (0.32) | TRPV1 | |
| SCHEMBL13291798 | 0.91 | TRPV1 (0.32) | TRPV1 | |
| SCHEMBL13291803 | 0.91 | TRPV1 (0.31) | TRPV1 | |
| SCHEMBL13383746 | 0.90 | TRPV1 (0.32) | TRPV1DRD4DRD2HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745495-B2 | Pyridine ketones with herbicidal effect | SYNGENTA CROP PROTECTION, INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-7745495-B2 | Pyridine ketones with herbicidal effect | SYNGENTA CROP PROTECTION, INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-7745495-B2 | Pyridine ketones with herbicidal effect | SYNGENTA CROP PROTECTION, INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-20090197767-A1 | PYRIDINE KETONES WITH HERBICIDAL EFFECT | SYNGENTA CROP PROTECTION, INC. (US) | 2009-08-06 | — | — | US | disclosed |
| US-20090197767-A1 | PYRIDINE KETONES WITH HERBICIDAL EFFECT | SYNGENTA CROP PROTECTION, INC. (US) | 2009-08-06 | — | — | US | disclosed |
| US-20090197767-A1 | PYRIDINE KETONES WITH HERBICIDAL EFFECT | SYNGENTA CROP PROTECTION, INC. (US) | 2009-08-06 | — | — | US | disclosed |
| EP-1828132-B1 | PYRIDINE KETONES WITH HERBICIDAL EFFECT | SYNGENTA PARTICIPATIONS AG (CH) | 2008-11-19 | — | — | EP | disclosed |
| EP-1886561-A1 | Method of protecting crop plants from herbicidal injury caused by HPPD-inhibitor herbicides | Syngenta Limited (GB) | 2008-02-13 | — | — | EP | disclosed |
| WO-2008009394-A2 | METHOD OF PROTECTING CROP PLANTS FROM HERBICIDAL INJURY CAUSED BY HPPD-INHIBITOR HERBICIDES | SYNGENTA LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |
| EP-1828132-A1 | PYRIDINE KETONES WITH HERBICIDAL EFFECT | Syngeta Participations AG (CH) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006066871-A1 | PYRIDINE KETONES WITH HERBICIDAL EFFECT | SYNGENTA PARTICIPATIONS AG (CH) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197767-A1 | PYRIDINE KETONES WITH HERBICIDAL EFFECT | CBR3, CBR1, AKR1C3 | TRPV1 2565/4885DRD4 589/4885DRD2 672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.