⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL5888995 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL9144467 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL11046687 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL3147380 | 0.87 | — | — | |
| Ammonia Solution, Strong SCHEMBL3151343 | 0.87 | — | — | |
| Ethylenediamine SCHEMBL8944357 | 0.74 | — | — | |
| SCHEMBL7209679 | 0.72 | — | — | |
| SCHEMBL5889169 | 0.72 | — | — | |
| SCHEMBL301443 | 0.72 | — | — | |
| SCHEMBL1504272 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756858-A | Nitric oxide donor type tetravalent platinum prodrug as well as preparation method and application thereof | 中国药科大学 | 2024-03-26 | — | — | CN | claimed |
| CN-117756858-A | Nitric oxide donor type tetravalent platinum prodrug as well as preparation method and application thereof | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-109563151-B | Methods and compositions for treating cancer | 瓦尔希伯伦私人肿瘤研究基金会 | 2023-03-07 | — | — | CN | disclosed |
| US-20210137874-A1 | MODIFIED PLATINUM COMPOUNDS AND THERAPEUTIC USES THEREOF | UNIV CALIFORNIA (US) | 2021-05-13 | — | — | US | disclosed |
| CN-109563151-A | Methods and compositions for treating cancer | 瓦尔希伯伦私人肿瘤研究基金会 | 2019-04-02 | — | — | CN | disclosed |
| WO-2018175601-A1 | MODIFIED PLATINUM COMPOUNDS AND THERAPEUTIC USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-09-27 | — | — | WO | disclosed |
| CN-106461641-A | Light-up probes based on fluorogens with aggregation induced emission characteristics for cellular imaging and drug screening | 新加坡国立大学 | 2017-02-22 | — | — | CN | disclosed |
| EP-0186085-A2 | Platinum complexes | AMERICAN CYANAMID COMPANY (US) | 1986-07-02 | — | — | EP | disclosed |
| US-4587331-A | ANTITUMOR | AMERICAN CYANAMID COMPANY (US) | 1986-05-06 | — | — | US | disclosed |