Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.71 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.53 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | HNF4A | P41235 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30461149 | 1.00 | FOLH1 (0.71) | FOLH1LTB4R2LTB4RPTPN1PTPN2 | |
| SCHEMBL27347541 | 0.87 | FOLH1 (0.54) | FOLH1LTB4R2LTB4RPTPN1PTPN2 | |
| SCHEMBL811976 | 0.87 | FOLH1 (0.67) | FOLH1LTB4R2LTB4RPTPN1PTPN2 | |
| SCHEMBL6777102 | 0.86 | PTPN1 (0.53) | FOLH1LTB4R2PTPN1PTPN2PTPN6 | |
| SCHEMBL4370807 | 0.86 | FOLH1 (0.74) | FOLH1AKR1C3AKR1C2 | |
| SCHEMBL9407400 | 0.86 | FOLH1 (0.75) | FOLH1LTB4R2LTB4RPTPN1PTPN2 | |
| SCHEMBL534889 | 0.83 | KDM4E (0.50) | FOLH1LTB4R2LTB4RHSD17B10MEN1 | |
| SCHEMBL3737187 | 0.83 | FOLH1 (0.71) | FOLH1LTB4R2LTB4RPTPN1PTPN2 | |
| SCHEMBL9388430 | 0.83 | FOLH1 (0.71) | FOLH1LTB4R2LTB4RPTPN1PTPN2 | |
| SCHEMBL28160677 | 0.83 | FOLH1 (0.71) | FOLH1LTB4R2LTB4RPTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332791-A | Preparation method of 2- (4' -azidomethylphenyl) benzoic acid | 珠海润都制药股份有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-115108906-A | Novel method for preparing 4 '-bromomethyl- [1,1' -biphenyl ] -2-tert-butyl formate | 临海市华南化工有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-114814041-A | Method for detecting bromoalkane genotoxic impurities in telmisartan by adopting liquid chromatograph-mass spectrometer | 浙江金立源药业有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-106008356-A | Preparation method for telmisartan | 浙江华海药业股份有限公司 | 2016-10-12 | — | — | CN | claimed |
| CN-105732483-A | Substituted dipine acid-4'-{[1,1'-biphenyl]-2-carboxylic acid}ester compounds and preparing method thereof | 青岛市黄岛区中医医院 | 2016-07-06 | — | — | CN | claimed |
| WO-2010018441-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF SUBSTANTIALLY PURE TELMISARTAN | CADILA PHARMACEUTICALS LTD. (IN) | 2010-02-18 | — | — | WO | claimed |
| CN-115466222-B | Preparation method of telmisartan intermediate | 江苏中邦制药有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-116332791-A | Preparation method of 2- (4' -azidomethylphenyl) benzoic acid | 珠海润都制药股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116332791-A | Preparation method of 2- (4' -azidomethylphenyl) benzoic acid | 珠海润都制药股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-218516219-U | Telmisartan intermediate filter-pressing and drying integrated machine | 河南华商药业有限公司 | 2023-02-24 | — | — | CN | disclosed |
| CN-115108906-A | Novel method for preparing 4 '-bromomethyl- [1,1' -biphenyl ] -2-tert-butyl formate | 临海市华南化工有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-114814041-A | Method for detecting bromoalkane genotoxic impurities in telmisartan by adopting liquid chromatograph-mass spectrometer | 浙江金立源药业有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-104768936-B | Prepare the method and its intermediate of Telmisartan | 上海特化医药科技有限公司 | 2017-07-28 | — | — | CN | disclosed |
| CN-1344712-A | Synthesis path of Timisatem | SHANGHAI INST OF PHARMACOLOGY (CN) | 2002-04-17 | — | — | CN | disclosed |
| EP-0726901-A4 | BENZO-FUSED MACROCYCLES PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 1997-01-22 | — | — | EP | disclosed |
| CN-1033584-C | Benzo-fused lactams that promote release of growth hormone | MERCK & CO INC (US) | 1996-12-18 | — | — | CN | disclosed |
| EP-0726901-A1 | BENZO-FUSED MACROCYCLES PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO. INC. (US) | 1996-08-21 | — | — | EP | disclosed |
| US-5470975-A | Dihydropyrimidine derivatives | E.R. SQUIBB & SONS, INC. (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0652869-A1 | IMIDAZOLE ETHERS HAVING A II ANTAGONIST ACTIVITY. | LUSO FARMACO INST (IT) | 1995-05-17 | — | — | EP | disclosed |
| EP-0323841-A2 | Substituted pyrrole, pyrazole and triazole angiotensin II antagonists | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-12 | — | — | EP | disclosed |