Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 15/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 14/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 14/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 8/20 | 0.39 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227481 | 0.89 | CCR1 (0.58) | CCR1 | |
| SCHEMBL15096080 | 0.86 | CCR1 (0.46) | CCR1FGFR2FGFR1FGFR3FGFR4 | |
| Hydrochloric Acid SCHEMBL15092786 | 0.86 | CCR1 (0.55) | CCR1 | |
| SCHEMBL26188308 | 0.78 | CCR1 (0.47) | CCR1 | |
| SCHEMBL3225786 | 0.78 | CCR1 (0.53) | CCR1FYN | |
| SCHEMBL1637661 | 0.77 | CCR1 (0.72) | CCR1 | |
| Hydrochloric Acid SCHEMBL3227494 | 0.76 | CCR1 (0.71) | CCR1 | |
| SCHEMBL16500309 | 0.75 | CCR1 (0.51) | CCR1 | |
| SCHEMBL13456458 | 0.75 | CCR1 (0.44) | CCR1 | |
| SCHEMBL3224268 | 0.75 | CCR1 (0.42) | CCR1TGFBR1FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069396-A1 | 4-AMINO-3-(IMIDAZOLYL)-PYRAZOLO[3,4-D]PYRIMIDINES | CHEMOCENTRYX, INC. (US) | 2010-03-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069396-A1 | 4-AMINO-3-(IMIDAZOLYL)-PYRAZOLO[3,4-D]PYRIMIDINES | CCR1, CCR3, CCR4 | CCR1 1/4885FGFR2 3356/4885FGFR1 2208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.