Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 2/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.43 |
| ▸ | GLS | O94925 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3234422 | 1.00 | ROCK1 (0.46) | ROCK1NTRK1NTRK2GLSMAPT | |
| SCHEMBL3235119 | 0.99 | ROCK1 (0.47) | ROCK1NTRK1NTRK2GLSMAPT | |
| SCHEMBL3229474 | 0.96 | ROCK1 (0.47) | ROCK1NTRK1NTRK2GLSMAPT | |
| SCHEMBL3235068 | 0.94 | ROCK1 (0.48) | ROCK1NTRK1NTRK2GLSMAPT | |
| SCHEMBL3237731 | 0.89 | ROCK1 (0.45) | ROCK1NTRK1NTRK2GLSMAPT | |
| SCHEMBL3242621 | 0.88 | ROCK1 (0.45) | ROCK1NTRK1NTRK2GLSMAPT | |
| SCHEMBL3232672 | 0.88 | ROCK1 (0.48) | ROCK1NTRK1NTRK2GLSMAPT | |
| SCHEMBL3232644 | 0.88 | PLA2G4B (0.50) | ROCK1NTRK1NTRK2GLSMAPT | |
| SCHEMBL3239734 | 0.88 | ROCK1 (0.49) | ROCK1NTRK1NTRK2GLSMAPT | |
| SCHEMBL3236167 | 0.88 | ROCK1 (0.45) | ROCK1NTRK1NTRK2GLSMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024422-A1 | AMIDE COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-04 | — | — | WO | disclosed |