Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 13/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3232600 | 0.89 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3231848 | 0.85 | PDE4B (0.52) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3234862 | 0.82 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL3240498 | 0.82 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL3236257 | 0.81 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3235972 | 0.80 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL3260690 | 0.80 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3236840 | 0.80 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3239951 | 0.79 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2371367 | 0.79 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029299-A1 | PYRIMIDINONE DERIVATIES FOR USE AS MEDICAMENTS | BIOLIPOX AB (SE) | 2010-03-18 | — | — | WO | disclosed |