SCHEMBL3236384

SCHEMBL3236384

COC(=O)C(NC(=O)c1cc(-c2ccc(NC(=O)Nc3c(F)cccc3F)c(C)c2)no1)C(C)C.Cc1cc(-c2cc(C(=O)O)on2)ccc1NC(=O)Nc1c(F)cccc1F

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CSGALNACT1 Q8TDX6 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2296139 0.97 CSGALNACT1 (0.60) CSGALNACT1
SCHEMBL2297537 0.90 CSGALNACT1 (0.71) CSGALNACT1
SCHEMBL2296703 0.88 CSGALNACT1 (0.53) CSGALNACT1
SCHEMBL2293743 0.86 CSGALNACT1 (0.49) CSGALNACT1
SCHEMBL2295284 0.86 CSGALNACT1 (0.69) CSGALNACT1
SCHEMBL2294270 0.85 CSGALNACT1 (0.59) CSGALNACT1
SCHEMBL2298578 0.85 CSGALNACT1 (0.66) CSGALNACT1
SCHEMBL2296615 0.85 CSGALNACT1 (0.49) CSGALNACT1
SCHEMBL2299208 0.83 CSGALNACT1 (0.62) CSGALNACT1
SCHEMBL3237048 0.83 CSGALNACT1 (0.67) CSGALNACT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010023609-A1 OXAZOLE, OXADIAZOLE AND THIAZOLE DERIVATIVES AS DIACYLGLYCEROL ACYLTRANFERASE INHIBITORS PIRAMAL LIFE SCIENCES LIMITED (IN) 2010-03-04 WO disclosed