Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 2/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237677 | 1.00 | ROCK1 (0.45) | ROCK1CSNK1DNTRK1NTRK2MAPT | |
| SCHEMBL3236337 | 0.97 | ROCK1 (0.45) | ROCK1CSNK1DNTRK1NTRK2MAPT | |
| SCHEMBL3236340 | 0.97 | ROCK1 (0.45) | ROCK1CSNK1DNTRK1NTRK2MAPT | |
| SCHEMBL3242655 | 0.95 | ROCK1 (0.46) | ROCK1CSNK1DNTRK1NTRK2MAPT | |
| SCHEMBL3242651 | 0.95 | ROCK1 (0.46) | ROCK1CSNK1DNTRK1NTRK2MAPT | |
| SCHEMBL3231621 | 0.92 | ROCK1 (0.45) | ROCK1CSNK1DNTRK1NTRK2MAPT | |
| SCHEMBL3242939 | 0.92 | ROCK1 (0.45) | ROCK1CSNK1DNTRK1NTRK2MAPT | |
| SCHEMBL3242941 | 0.92 | ROCK1 (0.45) | ROCK1CSNK1DNTRK1NTRK2MAPT | |
| SCHEMBL3231616 | 0.92 | ROCK1 (0.45) | ROCK1CSNK1DNTRK1NTRK2MAPT | |
| SCHEMBL3235455 | 0.91 | ROCK1 (0.45) | ROCK1CSNK1DNTRK1NTRK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024422-A1 | AMIDE COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-04 | — | — | WO | disclosed |