Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 4/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.58 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | FECH | P22830 | 1/20 | 0.44 |
| ▸ | CLK3 | P49761 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3229971 | 1.00 | PLK1 (0.58) | PLK1HDAC4HDAC1HDAC6HDAC3 | |
| SCHEMBL3235452 | 0.92 | PLK1 (0.58) | PLK1HDAC4HDAC1HDAC6HDAC3 | |
| SCHEMBL3235458 | 0.92 | PLK1 (0.58) | PLK1HDAC4HDAC1HDAC6HDAC3 | |
| SCHEMBL3238843 | 0.91 | PLK1 (0.57) | PLK1HDAC4HDAC1HDAC6HDAC3 | |
| SCHEMBL3238856 | 0.91 | PLK1 (0.57) | PLK1HDAC4HDAC1HDAC6HDAC3 | |
| SCHEMBL3235536 | 0.89 | PLK1 (0.53) | PLK1HDAC4HDAC1HDAC6HDAC3 | |
| SCHEMBL3235503 | 0.89 | PLK1 (0.53) | PLK1HDAC4HDAC1HDAC6HDAC3 | |
| SCHEMBL3231809 | 0.89 | HDAC4 (0.54) | PLK1HDAC4HDAC1HDAC6HDAC3 | |
| SCHEMBL3231821 | 0.89 | HDAC4 (0.54) | PLK1HDAC4HDAC1HDAC6HDAC3 | |
| SCHEMBL3236640 | 0.88 | PLK1 (0.52) | PLK1HDAC4HDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7744889-B2 | Alpha, beta-unsaturated sulfoxides for treating proliferative disorders | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2010-06-29 | — | — | US | disclosed |