⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389314 | 0.87 | — | — | |
| SCHEMBL3385868 | 0.84 | — | — | |
| SCHEMBL3384112 | 0.82 | — | — | |
| SCHEMBL13358953 | 0.76 | — | — | |
| SCHEMBL17062371 | 0.75 | — | — | |
| SCHEMBL13194890 | 0.74 | — | — | |
| SCHEMBL15718914 | 0.70 | — | — | |
| SCHEMBL15719821 | 0.68 | — | — | |
| SCHEMBL1988986 | 0.65 | — | — | |
| SCHEMBL11383997 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7744968-B2 | Cyclobutane and spiro[3.3]heptane compounds | MERCK PATENT GMBH (DE) | 2010-06-29 | — | — | US | disclosed |
| EP-1926798-B1 | CYCLOBUTANE AND SPIRO[3.3]HEPTANE COMPOUNDS | MERCK PATENT GMBH (DE) | 2009-09-30 | — | — | EP | disclosed |
| US-20080206490-A1 | Cyclobutane and Spiro[3.3]Heptane Compounds | MERCK PATENT GMBH (DE) | 2008-08-28 | — | — | US | disclosed |
| EP-1926798-A1 | CYCLOBUTANE AND SPIROÝ3.3¨HEPTANE COMPOUNDS | Merck Patent GmbH (DE) | 2008-06-04 | — | — | EP | disclosed |
| WO-2007033732-A1 | CYCLOBUTANE AND SPIRO[3.3]HEPTANE COMPOUNDS | MERCK PATENT GMBH (DE) | 2007-03-29 | — | — | WO | disclosed |