Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 16/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.75 |
| ▸ | GAA | P10253 | 8/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.75 |
| ▸ | CASP1 | P29466 | 5/20 | 0.75 |
| ▸ | RECQL | P46063 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 6/20 | 0.65 |
| ▸ | CASP7 | P55210 | 4/20 | 0.65 |
| ▸ | GLA | P06280 | 3/20 | 0.65 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.62 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20657021 | 0.94 | KDM4E (0.77) | KDM4EALDH1A1GAAHSD17B10CASP1 | |
| SCHEMBL12135861 | 0.91 | KDM4E (0.62) | KDM4EALDH1A1GAAHSD17B10CASP1 | |
| SCHEMBL12135715 | 0.90 | KDM4E (0.61) | KDM4EALDH1A1GAAHSD17B10CASP1 | |
| SCHEMBL3329623 | 0.90 | KDM4E (0.68) | KDM4EALDH1A1GAAHSD17B10CASP1 | |
| SCHEMBL13461414 | 0.89 | KDM4E (0.60) | KDM4EALDH1A1GAAHSD17B10CASP1 | |
| SCHEMBL12135860 | 0.88 | KDM4E (0.59) | KDM4EALDH1A1GAAHSD17B10CASP1 | |
| SCHEMBL12135863 | 0.88 | KDM4E (0.59) | KDM4EALDH1A1GAAHSD17B10CASP1 | |
| SCHEMBL3323327 | 0.87 | KDM4E (0.79) | KDM4EALDH1A1GAAHSD17B10CASP1 | |
| SCHEMBL12135812 | 0.86 | KDM4E (0.62) | KDM4EALDH1A1GAAHSD17B10CASP1 | |
| SCHEMBL15536537 | 0.85 | KDM4E (0.74) | KDM4EALDH1A1GAAHSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025251988-A9 | REAGENT COMBINATION OR KIT FOR CONSTRUCTING EMBRYOID AND USE THEREOF | 广州国家实验室 | 2026-05-15 | — | — | WO | claimed |
| EP-4356373-B1 | IMPROVED STABILITY OF INTER-CHANNEL TIME DIFFERENCE (ITD) ESTIMATOR FOR COINCIDENT STEREO CAPTURE | ERICSSON TELEFON AB L M (SE) | 2026-04-29 | — | — | EP | claimed |
| EP-4678739-A1 | IN VITRO METHOD FOR OBTAINING CORTICAL BRAIN ORGANOIDS, CORTICAL BRAIN ORGANOIDS AND USES THEREOF | Fundación Pública Andaluza Progreso Y Salud (ES) | 2026-01-14 | — | — | EP | claimed |
| US-20250340837-A1 | CELLS | UNIVERSITY OF GENEVA (CH) | 2025-11-06 | — | — | US | claimed |
| US-20250145948-A1 | METHOD FOR ASSESSING DIFFERENTIATION POTENTIAL OF CELLS IN CULTURE BROTH IN DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO NEURAL CELLS OF MIDBRAIN FLOOR PLATE REGION | Sumitomo Pharma Co., Ltd. (JP) | 2025-05-08 | — | — | US | claimed |
| WO-2025085826-A1 | ACTIVATION OF ORL1: A NOVEL THERAPY TO PREVENT HEART FAILURE PROGRESSION | BAYLOR COLLEGE OF MEDICINE (US) | 2025-04-24 | — | — | WO | claimed |
| EP-4504916-A1 | CELLS | University of Geneva (CH) | 2025-02-12 | — | — | EP | claimed |
| US-20240417692-A1 | DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS INTO PANCREATIC ENDOCRINE CELLS USING HB9 REGULATORS | JANSSEN BIOTECH, INC. (US) | 2024-12-19 | — | — | US | claimed |
| EP-4477746-A1 | METHOD FOR ASSESSING DIFFERENTIATION POTENTIAL OF CELLS IN CULTURE BROTH IN DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO NEURAL CELLS OF MIDBRAIN FLOOR PLATE REGION | Sumitomo Pharma Co., Ltd. (JP) | 2024-12-18 | — | — | EP | claimed |
| CN-118679244-A | Method for determining differentiation ability of cells in culture solution in differentiation of neural cells from pluripotent stem cells into midbrain floor region | 住友制药株式会社 | 2024-09-20 | — | — | CN | claimed |
| EP-2938723-B1 | DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS INTO PANCREATIC ENDOCRINE CELLS USING HB9 REGULATORS | JANSSEN BIOTECH INC (US) | 2023-02-01 | — | — | EP | claimed |
| US-20220348921-A1 | p63 INACTIVATION FOR THE TREATMENT OF HEART FAILURE | BAYLOR COLLEGE OF MEDICINE | 2022-11-03 | — | — | US | claimed |
| CN-114317401-B | Method for promoting long-term stable passage of islet precursor cells | 浙江大学 | 2022-10-04 | — | — | CN | claimed |
| CN-109392702-B | Method for artificially breeding normal cane shoots | 中国计量大学 | 2022-09-20 | — | — | CN | claimed |
| US-11421229-B2 | p63 inactivation for the treatment of heart failure | BAYLOR COLLEGE OF MEDICINE (US) | 2022-08-23 | — | — | US | claimed |
| CN-114836369-A | Method for differentiating induced pluripotent stem cells into pancreatic islets and application of induced pluripotent stem cells in treatment of type I diabetes | 呈诺再生医学科技(北京)有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-114807015-A | Induction method for promoting islet alpha cells to be converted into beta cells and application thereof | 呈诺再生医学科技(北京)有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-114540278-A | Microvessel in-vitro culture method and culture solution | 青岛大学 | 2022-05-27 | — | — | CN | claimed |
| CN-114317401-A | Method for promoting long-term stable passage of islet precursor cells | 浙江大学 | 2022-04-12 | — | — | CN | claimed |
| EP-3954759-A1 | USE OF SMALL MOLECULES TO ENHANCE MAFA EXPRESSION IN PANCREATIC ENDOCRINE CELLS | Janssen Biotech, Inc. (US) | 2022-02-16 | — | — | EP | claimed |