⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13953066 | 0.79 | — | — | |
| SCHEMBL23113870 | 0.79 | — | — | |
| SCHEMBL798415 | 0.79 | — | — | |
| SCHEMBL15309710 | 0.79 | — | — | |
| SCHEMBL5184982 | 0.76 | — | — | |
| SCHEMBL22190428 | 0.76 | — | — | |
| SCHEMBL14923942 | 0.76 | — | — | |
| SCHEMBL2076983 | 0.74 | — | — | |
| SCHEMBL2191702 | 0.74 | — | — | |
| SCHEMBL3399798 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399489-B2 | Antibacterial piperdine derivatives | ASTRAZENECA AB (GB) | 2013-03-19 | — | — | US | disclosed |
| US-20100179150-A1 | ANTIBACTERIAL PIPERDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2010-07-15 | — | — | US | disclosed |