Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3254646 | 0.92 | SCN9A (0.74) | SCN9A | |
| SCHEMBL3250601 | 0.91 | SCN9A (0.70) | SCN9A | |
| SCHEMBL3239014 | 0.84 | SCN9A (0.67) | SCN9A | |
| SCHEMBL17722095 | 0.84 | SCN9A (1.00) | SCN9A | |
| SCHEMBL3240824 | 0.84 | SCN9A (0.71) | SCN9A | |
| SCHEMBL3235659 | 0.83 | SCN9A (0.75) | SCN9A | |
| SCHEMBL3248254 | 0.83 | SCN9A (0.65) | SCN9A | |
| SCHEMBL3251924 | 0.83 | SCN9A (0.61) | SCN9A | |
| SCHEMBL17722153 | 0.82 | SCN9A (1.00) | SCN9A | |
| SCHEMBL17722057 | 0.81 | SCN9A (1.00) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022055-A2 | INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | AMGEN INC. (US) | 2010-02-25 | — | — | WO | claimed |
| WO-2010022055-A2 | INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | AMGEN INC. (US) | 2010-02-25 | — | — | WO | disclosed |