Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | PLK4 | O00444 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240242 | 1.00 | CYP3A4 (0.70) | CYP3A4CRBNTRPV1KDM4EALDH1A1 | |
| SCHEMBL2489645 | 0.89 | CYP3A4 (0.73) | CYP3A4CRBNTRPV1CYP17A1ERBB2 | |
| SCHEMBL2489644 | 0.89 | CYP3A4 (0.73) | CYP3A4CRBNTRPV1CYP17A1ERBB2 | |
| SCHEMBL6832654 | 0.85 | CYP3A4 (0.49) | CYP3A4PDE4BERBB2TNFRSF1A | |
| SCHEMBL2127562 | 0.85 | CYP3A4 (0.76) | CYP3A4CRBNTRPV1TNFRSF1APADI4 | |
| SCHEMBL1542924 | 0.85 | CYP3A4 (0.76) | CYP3A4CRBNTRPV1TNFRSF1APADI4 | |
| SCHEMBL2127702 | 0.84 | CYP3A4 (0.75) | CYP3A4CRBNTRPV1CYP17A1BRD4 | |
| SCHEMBL482574 | 0.84 | CYP3A4 (0.75) | CYP3A4CRBNTRPV1ALDH1A1TNFRSF1A | |
| SCHEMBL2127697 | 0.84 | CYP3A4 (0.75) | CYP3A4CRBNTRPV1CYP17A1BRD4 | |
| SCHEMBL482573 | 0.84 | CYP3A4 (0.75) | CYP3A4CRBNTRPV1ALDH1A1TNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100158860-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | STEINER SANDRA | 2010-06-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158860-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | RFC1, RRP1B, RRBP1 | CYP3A4 978/4885CRBN 1341/4885TRPV1 4760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.