SCHEMBL3242792

SCHEMBL3242792

C=CC(=O)OCCNC(=O)NC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.48
HPGD P15428 2/20 0.48
ALDH1A1 P00352 5/20 0.48
TP53 P04637 3/20 0.48
HIF1A Q16665 3/20 0.48
CYP3A4 P08684 2/20 0.48
HSD17B10 Q99714 1/20 0.48
THRB P10828 2/20 0.41
MAPK1 P28482 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KEAP1 Q14145 1/20 0.34
NFE2L2 Q16236 1/20 0.34
KMT2A Q03164 1/20 0.32
MTNR1A P48039 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
RAB9A P51151 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5663537 0.88 TSHR (0.56) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL12570601 0.86 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL18364747 0.85 ATM (0.45) ALDH1A1KEAP1NFE2L2KMT2AMTNR1A
SCHEMBL25437489 0.84 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL30537436 0.84 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL13051497 0.84 TSHR (0.52) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL3256143 0.84 TSHR (0.56) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL12570765 0.81 TSHR (0.59) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL15431643 0.81 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL12570592 0.81 TSHR (0.64) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2657304-B1 AZO DYE, OCULAR LENS MATERIAL, METHOD FOR PRODUCING OCULAR LENS MATERIAL, AND OCULAR LENS MENICON CO LTD (JP) 2022-12-07 EP disclosed
EP-3521927-B1 POSITIVE WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR MANUFACTURING THE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2021-10-27 EP disclosed
US-10649337-B2 Positive type lithographic printing plate precursor, method of producing same, and method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2020-05-12 US disclosed
EP-3521927-A1 POSITIVE PLANOGRAPHIC PRINTING ORIGINAL PLATE AND METHOD FOR MANUFACTURING SAME, AND METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2019-08-07 EP disclosed
US-20190212652-A1 POSITIVE TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PRODUCING SAME, AND METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2019-07-11 US disclosed
EP-1975707-B1 Curable composition and planographic printing plate precursor FUJIFILM CORP (JP) 2017-07-19 EP disclosed
EP-2657304-A1 AZO DYE, OCULAR LENS MATERIAL, METHOD FOR PRODUCING OCULAR LENS MATERIAL, AND OCULAR LENS Menicon Co., Ltd. (JP) 2013-10-30 EP disclosed
EP-1705004-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2013-09-25 EP disclosed
US-7964334-B2 Mixture containing urea compound as photoinitiator; curing by exposure to laser light FUJIFILM CORPORATION (JP) 2011-06-21 US disclosed
US-7825168-B2 Ink composition, ink jet recording method, method of producing planographic printing plate, and planographic printing plate FUJIFILM CORPORATION (JP) 2010-11-02 US disclosed
EP-1136886-B1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORP (JP) 2010-05-19 EP disclosed
US-20090246693-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20080241744-A1 CURABLE COMPOSITION AND PLANOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080241744-A1 CURABLE COMPOSITION AND PLANOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
EP-1975707-A1 Curable composition and planographic printing plate precursor Fujifilm Corporation (JP) 2008-10-01 EP disclosed
US-20070060665-A1 polymerization initiator and a monofunctional (meth)acrylate having a CONH bond in the molecule; acrylate monomer having an amide or carbamate or urea in the side chain; hydrogen bonding increases curing speed and flexibility of film FUJI PHOTO FILM CO., LTD. 2007-03-15 US disclosed
EP-1705004-A1 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2006-09-27 EP disclosed
US-6517987-B2 Mixture of 1,2-naphthoquinone-2-diazide-5-sulfonic acid and polymer FUJI PHOTO FILM CO., LTD. (JP) 2003-02-11 US disclosed
US-20010041299-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORPORATION (JP) 2001-11-15 US disclosed
EP-1136886-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate Fuji Photo Film Co., Ltd. (JP) 2001-09-26 EP disclosed