Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6344599 | 1.00 | GAA (0.44) | GAACES2CES1SCN5ASCN9A | |
| SCHEMBL29456136 | 1.00 | GAA (0.44) | GAACES2CES1SCN5ASCN9A | |
| SCHEMBL29456058 | 1.00 | GAA (0.44) | GAACES2CES1SCN5ASCN9A | |
| SCHEMBL28727429 | 0.98 | GAA (0.43) | GAACES2CES1SCN5ASCN9A | |
| SCHEMBL28727398 | 0.98 | GAA (0.43) | GAACES2CES1SCN5ASCN9A | |
| SCHEMBL28729552 | 0.98 | GAA (0.43) | GAACES2CES1SCN5ASCN9A | |
| SCHEMBL28727674 | 0.98 | GAA (0.43) | GAACES2CES1SCN5ASCN9A | |
| SCHEMBL28729541 | 0.98 | GAA (0.43) | GAACES2CES1SCN5ASCN9A | |
| SCHEMBL28727663 | 0.98 | GAA (0.43) | GAACES2CES1SCN5ASCN9A | |
| SCHEMBL28727490 | 0.98 | GAA (0.43) | GAACES2CES1SCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039531-A1 | THERAPEUTIC COMPOUNDS | RESOLVYX PHARMACEUTICALS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |