1,4-Butanediol

1,4-Butanediol

SCHEMBL324322

OCCCCO.OCCCCO

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.58
TSHR P16473 5/20 0.54
ALDH1A1 P00352 3/20 0.54
LMNA P02545 2/20 0.54
HSD17B10 Q99714 1/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
GPR84 Q9NQS5 1/20 0.44
FFAR1 O14842 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
CAMK2A Q9UQM7 1/20 0.40
MIF P14174 1/20 0.37
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
CA12 O43570 2/20 0.35
CA9 Q16790 2/20 0.35
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL30932429 1.00
1,4-Butanediol SCHEMBL18642519 1.00 SMN1; SMN2 (0.58) SMN1; SMN2TSHRALDH1A1LMNAHSD17B10
1,4-Butanediol SCHEMBL15086 1.00
1,4-Butanediol SCHEMBL18642509 1.00 SMN1; SMN2 (0.58) SMN1; SMN2TSHRALDH1A1LMNAHSD17B10
1,4-Butanediol SCHEMBL23116601 0.94
SCHEMBL21462773 0.94 TSHR (0.61) SMN1; SMN2TSHRALDH1A1LMNAHSD17B10
1,4-Butanediol SCHEMBL21611909 0.94
1,4-Butanediol SCHEMBL21630075 0.94 TSHR (0.61) SMN1; SMN2TSHRALDH1A1LMNAHSD17B10
1,4-Butanediol SCHEMBL21542368 0.94
SCHEMBL15847768 0.94 TSHR (0.61) SMN1; SMN2TSHRALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111040111-A Antistatic thermoplastic polyurethane and preparation method thereof 苏州纤创智造新材料科技有限公司 2020-04-21 CN claimed
CN-111019085-A Antistatic thermoplastic polyurethane and preparation method thereof 苏州纤创智造新材料科技有限公司 2020-04-17 CN claimed
EP-4387602-A1 POTASSIUM HYDROGEN SALTS OF ALKYLHYDROXAMATES AND COMPOSITIONS COMPRISING THE SAME Inolex Investment Corporation (US) 2024-06-26 EP disclosed
EP-4240314-A1 BIOBASED GLYCERYL HEPTANOATE ESTER COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME Inolex Investment Corporation (US) 2023-09-13 EP disclosed
WO-2023054921-A1 COLOR COSMETIC COMPOSITION COMPRISING POLYOL-OIL EMULSION 코스맥스 주식회사 2023-04-06 WO disclosed
EP-4152930-A2 BIOBASED ALKYL GLYCERYL ETHERS AND METHODS OF MAKING AND USING THE SAME Inolex Investment Corporation (US) 2023-03-29 EP disclosed
WO-2023022899-A1 POTASSIUM HYDROGEN SALTS OF ALKYLHYDROXAMATES AND COMPOSITIONS COMPRISING THE SAME INOLEX INVESTMENT CORPORATION (US) 2023-02-23 WO disclosed
EP-4025675-A1 A PERFUME OIL MIXTURE Symrise AG (DE) 2022-07-13 EP disclosed
WO-2022098829-A1 BIOBASED GLYCERYL HEPTANOATE ESTER COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME INOLEX INVESTMENT CORPORATION (US) 2022-05-12 WO disclosed
EP-3982910-A1 A COOLING PREPARATION Symrise AG (DE) 2022-04-20 EP disclosed
US-11267933-B2 Method of preparing poly(ether ester) copolymer LG CHEM, LTD. (KR) 2022-03-08 US disclosed
EP-1365729-A4 ULTRA-STABLE COMPOSITION COMPRISING MORINGA OIL AND ITS DERIVATIVES AND USES THEREOF INT FLORA TECHNOLOGIES LTD (US) 2004-03-17 EP disclosed
EP-1365729-A1 ULTRA-STABLE COMPOSITION COMPRISING MORINGA OIL AND ITS DERIVATIVES AND USES THEREOF International Flora Technologies, Ltd. (US) 2003-12-03 EP disclosed
WO-2003011234-A1 ULTRA-STABLE COMPOSITION COMPRISING MORINGA OIL AND ITS DERIVATIVES AND USES THEREOF INTERNATIONAL FLORA TECHNOLOGIES, LTD. (US) 2003-02-13 WO disclosed
CN-2463169-Y Elastic composite material JIFA XINGYE CO LTD (CN) 2001-12-05 CN disclosed
US-5252431-A Light sensitive layer and silicone rubber layer; spraying pressurized liquid on the surface to remove the rubber layer FUJI PHOTO FILM CO., LTD. (JP) 1993-10-12 US disclosed
EP-0163150-B1 ABSORBENT BODIES COMPRISING AN INTERPENETRATING POLYMERIC NETWORK COMPRISING CROSS-LINKED POLYELECTROLYTES PERSONAL PRODUCTS COMPANY (US) 1990-03-21 EP disclosed
US-4613543-A Interpenetrating polymeric network foams comprising crosslinked polyelectrolytes PERSONAL PRODUCTS COMPANY (US) 1986-09-23 US disclosed
EP-0163150-A1 Absorbent bodies comprising an interpenetrating Polymeric network comprising cross-linked polyelectrolytes PERSONAL PRODUCTS COMPANY (US) 1985-12-04 EP disclosed
US-4294998-A CRYSTALLIZATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-10-13 US disclosed