Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 13/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454518 | 1.00 | CACNA1B (0.64) | CACNA1BGAAHPGDPKMPKLR | |
| SCHEMBL67290 | 1.00 | CACNA1B (0.64) | CACNA1BGAAHPGDPKMPKLR | |
| SCHEMBL16498004 | 1.00 | CACNA1B (0.64) | CACNA1BGAAHPGDPKMPKLR | |
| SCHEMBL66447 | 1.00 | CACNA1B (0.64) | CACNA1BGAAHPGDPKMPKLR | |
| SCHEMBL66912 | 0.83 | CACNA1B (0.59) | CACNA1BGAAHPGDPKMPKLR | |
| SCHEMBL16498033 | 0.83 | CACNA1B (0.59) | CACNA1BGAAHPGDPKMPKLR | |
| SCHEMBL67936 | 0.83 | CACNA1B (0.59) | CACNA1BGAAHPGDPKMPKLR | |
| SCHEMBL2844227 | 0.82 | CACNA1B (0.71) | CACNA1B | |
| SCHEMBL2849919 | 0.82 | CACNA1B (0.82) | CACNA1BGAAHPGD | |
| SCHEMBL2847018 | 0.82 | CACNA1B (0.82) | CACNA1BGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010062927-A2 | NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA(C)PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS | ABBOTT LABORATORIES (US) | 2010-06-03 | — | — | WO | disclosed |