Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Hydantoin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydantoin SCHEMBL29936676 | 1.00 | — | — | |
| Hydantoin SCHEMBL1266954 | 0.97 | — | — | |
| Hydantoin SCHEMBL27705088 | 0.97 | CRBN (0.52) | — | |
| Hydantoin SCHEMBL7285865 | 0.97 | — | — | |
| Hydantoin SCHEMBL27690 | 0.97 | — | — | |
| Hydantoin SCHEMBL10408014 | 0.94 | — | — | |
| Hydantoin SCHEMBL5673206 | 0.94 | — | — | |
| Hydantoin SCHEMBL8638709 | 0.94 | — | — | |
| Hydantoin SCHEMBL22371823 | 0.94 | — | — | |
| Hydantoin SCHEMBL11595715 | 0.94 | CRBN (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8229569-A | — | — | None | — | — | JP | disclosed |
| CN-110150289-A | A kind of Treatment of Industrial Water antimildew and antibacterial liquid and preparation method thereof | 河北利仕化学科技有限公司 | 2019-08-23 | — | — | CN | disclosed |
| EP-2341777-B1 | ANTIMICROBIAL OXAZOLIDINONE, HYDANTOIN AND IMIDAZOLIDINONE COMPOSITIONS | NOVABAY PHARMACEUTICALS INC (US) | 2015-01-21 | — | — | EP | disclosed |
| US-8722715-B2 | Antimicrobial oxazolidinone, hydantoin and imidazolidinone compositions | NovaBay Pharmaceuticals (US) | 2014-05-13 | — | — | US | disclosed |
| US-20100137349-A1 | ANTIMICROBIAL OXAZOLIDINONE, HYDANTOIN AND IMIDAZOLIDINONE COMPOSITIONS | NOVABAY PHARMACEUTICALS, INC. | 2010-06-03 | — | — | US | disclosed |
| WO-2010054009-A1 | ANTIMICROBIAL OXAZOLIDINONE, HYDANTOIN AND IMIDAZOLIDINONE COMPOSITIONS | NOVABAY PHARMACEUTICALS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| EP-0742317-A1 | Method for inhibiting microbial growth in paper process systems | Calgon Corporation (US) | 1996-11-13 | — | — | EP | disclosed |
| JP-H08229569-A | TREATMENT OF AQUEOUS SLIME | HAKUTO CO LTD | 1996-09-10 | — | — | JP | disclosed |