Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 2/20 | 0.43 |
| ▸ | GABRD | O14764 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.43 |
| ▸ | GABRE | P78334 | 2/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19835436 | 0.85 | MAPK1 (0.50) | MAPK1NQO2ALDH1A1LCKGABRP | |
| SCHEMBL474122 | 0.84 | KDM4E (0.44) | MAPK1NQO2ALDH1A1MAPTKDM4E | |
| SCHEMBL29551416 | 0.84 | KDM4E (0.44) | MAPK1NQO2ALDH1A1MAPTKDM4E | |
| SCHEMBL10467645 | 0.83 | MAPK1 (0.52) | MAPK1NQO2ALDH1A1LCKGABRP | |
| SCHEMBL29425147 | 0.82 | GAA (0.42) | NQO2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL30031450 | 0.82 | MAPK1 (0.47) | MAPK1NQO2ALDH1A1LCKGABRP | |
| SCHEMBL21873493 | 0.82 | LCK (0.53) | MAPK1NQO2ALDH1A1LCKGABRP | |
| SCHEMBL3936135 | 0.82 | MAPK1 (0.47) | MAPK1NQO2ALDH1A1LCKGABRP | |
| SCHEMBL8495483 | 0.82 | GAA (0.42) | NQO2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL2217864 | 0.82 | GAA (0.42) | NQO2ALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059552-A1 | PROLYL HYDROXYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2010-05-27 | — | — | WO | disclosed |
| WO-2010059552-A1 | PROLYL HYDROXYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2010-05-27 | — | — | WO | disclosed |