SCHEMBL3244533

SCHEMBL3244533

O=[N+]([O-])c1cccc(CSSCc2cccc([N+](=O)[O-])c2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.65
LMNA P02545 2/20 0.59
ALDH1A1 P00352 6/20 0.55
HTT P42858 2/20 0.55
POLB P06746 2/20 0.55
HSP90AA1 P07900 1/20 0.53
MAPT P10636 2/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.52
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
RXFP1 Q9HBX9 1/20 0.51
EPHX1 P07099 1/20 0.50
ACHE P22303 1/20 0.50
CTSB P07858 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALOX15 P16050 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3240297 0.89 TSHR (0.65) TSHRLMNAALDH1A1HTTPOLB
SCHEMBL2716313 0.85 TSHR (0.61) TSHRLMNAALDH1A1HTTPOLB
SCHEMBL5521816 0.85 TSHR (0.61) TSHRLMNAALDH1A1HTTPOLB
SCHEMBL14873550 0.85 TSHR (0.61) TSHRLMNAALDH1A1HTTPOLB
SCHEMBL28180118 0.85 TSHR (0.61) TSHRLMNAALDH1A1HTTPOLB
SCHEMBL14785027 0.84 TSHR (0.59) TSHRLMNAALDH1A1HTTPOLB
SCHEMBL14060334 0.82 TSHR (0.57) TSHRLMNAALDH1A1HTTPOLB
SCHEMBL31317852 0.82 TSHR (0.57) TSHRLMNAALDH1A1HTTPOLB
SCHEMBL10918542 0.82 TSHR (0.71) TSHRLMNAALDH1A1HTTPOLB
SCHEMBL22190300 0.81 TSHR (0.56) TSHRLMNAALDH1A1HTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107325058-B Diaryl methylene disulfide compound and preparation method and application thereof 苏州大学 2020-07-24 CN disclosed
CN-107325058-A Two fragrant methylene disulfide compounds and preparation method and application 苏州大学 2017-11-07 CN disclosed
EP-1225205-B1 Carbon black reacted with diazonium salts and products CABOT CORP (US) 2010-10-06 EP disclosed
EP-1942156-B1 Carbon black reacted with diazonium salts and products CABOT CORP (US) 2010-04-14 EP disclosed
EP-1942156-A1 Carbon black reacted with diazonium salts and products Cabot Corporation (US) 2008-07-09 EP disclosed
US-7294185-B2 In absence of exterior applies electrical current; wear resistance CABOT CORPORATION (US) 2007-11-13 US disclosed
EP-0799281-B2 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORP (US) 2006-03-29 EP disclosed
US-20050034629-A1 In absence of exterior applies electrical current; wear resistance BELMONT JAMES A (US) 2005-02-17 US disclosed
US-6740151-B2 IN THE ABSENCE OF AN EXTERNALLY APPLIED ELECTRIC CURRENT SUFFICIENT TO REDUCE THE DIAZONIUM SALT AND ATTACH AN ORGANIC GROUP; IMPROVED ABRASION RESISTANCE. CABOT CORPORATION 2004-05-25 US disclosed
US-20030095914-A1 In the absence of an externally applied electric current sufficient to reduce the diazonium salt and attach an organic group; improved abrasion resistance. BELMONT JAMES A (US) 2003-05-22 US disclosed
US-6494946-B1 PROCESSES FOR PREPARING A CARBON BLACK PRODUCT HAVING AN ORGANIC GROUP ATTACHED TO THE CARBON BLACK. IN ONE PROCESS AT LEAST ONE DIAZONIUM SALT REACTS WITH A CARBON BLACK IN THE ABSENCE OF AN EXTERNALLY APPLIED ELECTRIC CURRENT SUFFICIENT CABOT CORPORATION 2002-12-17 US disclosed
EP-0799281-B1 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORP (US) 2002-07-24 EP disclosed
EP-1225205-A2 Carbon black reacted with diazonium salts and products CABOT CORPORATION (US) 2002-07-24 EP disclosed
US-6042643-A AS PIGMENT TO COLOR PLASTICS, PAPER, TEXTILE, RUBBER, AQUEOUS INKS CABOT CORPORATION (US) 2000-03-28 US disclosed
US-5900029-A COLORING FIBER OR TEXTILE CABOT CORPORATION (US) 1999-05-04 US disclosed
US-5851280-A Reaction of carbon black with diazonium salts, resultant carbon black products and their uses CABOT CORPORATION (US) 1998-12-22 US disclosed
EP-0799281-A1 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORPORATION (US) 1997-10-08 EP disclosed
WO-1996018688-A1 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORPORATION (US) 1996-06-20 WO disclosed