Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.81 |
| ▸ | PPARA | Q07869 | 5/20 | 0.81 |
| ▸ | PPARG | P37231 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237429 | 0.93 | PPARD (0.71) | PPARDPPARAPPARG | |
| SCHEMBL3241505 | 0.89 | PPARD (1.00) | PPARDPPARAPPARG | |
| SCHEMBL13292269 | 0.88 | PPARD (1.00) | PPARDPPARAPPARG | |
| SCHEMBL13292306 | 0.87 | PPARD (1.00) | PPARDPPARAPPARG | |
| SCHEMBL13292417 | 0.87 | PPARD (1.00) | PPARDPPARAPPARG | |
| SCHEMBL13292309 | 0.87 | PPARD (1.00) | PPARDPPARAPPARG | |
| SCHEMBL3230861 | 0.85 | PPARD (1.00) | PPARDPPARAPPARG | |
| SCHEMBL13292312 | 0.85 | PPARD (0.90) | PPARDPPARAPPARG | |
| SCHEMBL13292322 | 0.85 | PPARD (0.90) | PPARDPPARAPPARG | |
| SCHEMBL13292311 | 0.84 | PPARD (0.88) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745445-B2 | Compounds and compositions as PPAR modulators | IRM LLC (BM) | 2010-06-29 | — | — | US | disclosed |
| US-7745445-B2 | Compounds and compositions as PPAR modulators | IRM LLC (BM) | 2010-06-29 | — | — | US | disclosed |
| US-7745445-B2 | Compounds and compositions as PPAR modulators | IRM LLC (BM) | 2010-06-29 | — | — | US | disclosed |
| EP-1756062-A4 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2008-01-02 | — | — | EP | disclosed |
| US-20070259890-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2007-11-08 | — | — | US | disclosed |
| US-20070259890-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2007-11-08 | — | — | US | disclosed |
| US-20070259890-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2007-11-08 | — | — | US | disclosed |
| EP-1756062-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005113506-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2005-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259890-A1 | Compounds and Compositions as Ppar Modulators | PPARG, PPARD, PPARA | PPARD 2/4885PPARA 3/4885PPARG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.