Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 11/20 | 0.74 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CCR5 | P51681 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 5/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252824 | 1.00 | CCR1 (0.74) | CCR1CHRM2CCR5HRH1ADRA1D | |
| SCHEMBL653153 | 0.93 | CCR1 (0.73) | CCR1CHRM2CCR5HRH1ADRA1D | |
| SCHEMBL653152 | 0.93 | CCR1 (0.73) | CCR1CHRM2CCR5HRH1ADRA1D | |
| SCHEMBL651741 | 0.92 | CCR1 (0.69) | CCR1CHRM2CCR5 | |
| SCHEMBL651742 | 0.92 | CCR1 (0.69) | CCR1CHRM2CCR5 | |
| SCHEMBL654239 | 0.91 | CCR1 (0.76) | CCR1CHRM2CCR5HRH1ADRA1D | |
| SCHEMBL654238 | 0.91 | CCR1 (0.76) | CCR1CHRM2CCR5HRH1ADRA1D | |
| SCHEMBL10288021 | 0.91 | CCR1 (0.75) | CCR1CHRM2CCR5HRH1ADRA1D | |
| SCHEMBL651828 | 0.91 | CCR1 (0.73) | CCR1CHRM2CCR5HRH1ADRA1D | |
| SCHEMBL651827 | 0.91 | CCR1 (0.73) | CCR1CHRM2CCR5HRH1ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1669356-B1 | CCR1 Antagonists for the treatment of i.a demyelinating inflammatory disease | MILLENNIUM PHARM INC (US) | 2010-05-19 | — | — | EP | claimed |