Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 12/20 | 0.41 |
| ▸ | DRD2 | P14416 | 9/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239669 | 0.90 | CCR8 (0.46) | CCR8MTNR1BMTNR1ASMN1; SMN2HTR2B | |
| SCHEMBL3239661 | 0.90 | CCR8 (0.46) | CCR8MTNR1BMTNR1ASMN1; SMN2HTR2B | |
| SCHEMBL3252171 | 0.88 | CCR8 (0.46) | CCR8MTNR1BMTNR1ASMN1; SMN2HTR2B | |
| SCHEMBL3252168 | 0.88 | CCR8 (0.46) | CCR8MTNR1BMTNR1ASMN1; SMN2HTR2B | |
| SCHEMBL3239809 | 0.87 | CCR8 (0.43) | CCR8SMN1; SMN2 | |
| SCHEMBL3239699 | 0.77 | KCNH2 (0.55) | MTNR1BMTNR1A | |
| SCHEMBL3246398 | 0.77 | KCNH2 (0.52) | — | |
| SCHEMBL3246402 | 0.77 | KCNH2 (0.52) | — | |
| SCHEMBL5330379 | 0.75 | KCNH2 (0.45) | CCR8SMN1; SMN2 | |
| SCHEMBL5443493 | 0.75 | KCNH2 (0.45) | CCR8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799674-B1 | NEW PIPERIDINE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-05-05 | — | — | EP | claimed |