Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921697 | 0.86 | BTK (0.45) | BTKEGFRLCK | |
| SCHEMBL12354529 | 0.86 | BTK (0.45) | BTKEGFRLCK | |
| SCHEMBL1922018 | 0.85 | BTK (0.53) | BTKEGFRLCK | |
| SCHEMBL1921672 | 0.82 | BTK (0.47) | BTKEGFRLCK | |
| SCHEMBL1921902 | 0.82 | BTK (0.46) | BTKEGFRLCK | |
| SCHEMBL1923126 | 0.81 | KDM4C (0.51) | BTKEGFRLCK | |
| SCHEMBL1921470 | 0.81 | KDM4C (0.51) | BTKEGFRLCK | |
| SCHEMBL12354530 | 0.81 | KDM4C (0.51) | BTKEGFRLCK | |
| SCHEMBL1921723 | 0.81 | BTK (0.60) | BTKEGFRLCK | |
| SCHEMBL1921594 | 0.80 | BTK (0.56) | BTKEGFRLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010031791-A1 | NEW COMPOUNDS II | BIOVITRUM AB (PUBL) (SE) | 2010-03-25 | — | — | WO | disclosed |