SCHEMBL324675

SCHEMBL324675

CCC1CCCC1c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 9/20 0.43
HTR2B P41595 6/20 0.42
HTR2A P28223 4/20 0.42
MAOB P27338 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
GRIA4 P48058 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23185437 0.96 MEN1 (0.46) HTR2CHTR2BHTR2AMAOBMEN1
SCHEMBL7563619 0.87 HTR2C (0.40) HTR2CHTR2BHTR2AMAOBMEN1
SCHEMBL27846715 0.82 DPP4 (0.42) HTR2C
SCHEMBL15254847 0.80 MAOB (0.62) HTR2CHTR2BHTR2AMAOB
SCHEMBL8036763 0.80 MEN1 (0.46) HTR2CHTR2BHTR2AMAOBMEN1
SCHEMBL21535613 0.79 MAOB (0.44) HTR2CHTR2BHTR2AMAOB
SCHEMBL12505576 0.79 HTR2C (0.50) HTR2CHTR2BHTR2AMAOBGRIA4
SCHEMBL27347061 0.79 GRIA4 (0.37) HTR2CHTR2BHTR2AMAOBMEN1
SCHEMBL20348840 0.77 SLC6A2 (0.46) HTR2CHTR2BHTR2A
SCHEMBL839081 0.76 MEN1 (0.50) HTR2CHTR2BHTR2AMAOBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2590973-B1 SOLIFENACIN SALTS CRYSTAL PHARMA SAU (ES) 2016-08-31 EP disclosed
US-8765785-B2 Solifenacin salts CRYSTAL PHARMA, S.A.U. (ES) 2014-07-01 US disclosed
US-20130203804-A1 SOLIFENACIN SALTS CRYSTAL PHARMA, S.A.U. (ES) 2013-08-08 US disclosed
EP-2590973-A1 SOLIFENACIN SALTS Crystal Pharma S.A.U (ES) 2013-05-15 EP disclosed
WO-2012079583-A1 SYSTEM PROVIDING CONTROLLED DELIVERY OF GASEOUS CO FOR CARBONYLATION REACTIONS AARHUS UNIVERSITET (DK) 2012-06-21 WO disclosed
WO-2012004264-A1 SOLIFENACIN SALTS RAGACTIVES, S.L.U. (ES) 2012-01-12 WO disclosed
WO-2010031408-A2 GEL COMPOSITIONS AARHUS UNIVERSITET (DK) 2010-03-25 WO disclosed