Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.57 |
| ▸ | CNR1 | P21554 | 3/20 | 0.57 |
| ▸ | RPA1 | P27694 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909080 | 0.89 | CNR1 (0.59) | CNR2CNR1RPA1 | |
| SCHEMBL909361 | 0.89 | CNR2 (0.59) | CNR2CNR1 | |
| SCHEMBL8018768 | 0.88 | CNR2 (0.57) | CNR2CNR1RPA1 | |
| SCHEMBL2873006 | 0.88 | CNR2 (0.61) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL9160043 | 0.87 | CNR2 (0.60) | CNR2CNR1 | |
| SCHEMBL4632916 | 0.87 | CNR1 (0.59) | CNR2CNR1 | |
| SCHEMBL4910785 | 0.86 | CNR2 (0.47) | CNR2CNR1 | |
| SCHEMBL8013386 | 0.86 | CNR2 (0.58) | CNR2CNR1 | |
| SCHEMBL4633715 | 0.85 | CNR1 (0.63) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL8016462 | 0.85 | CNR2 (0.57) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658546-B1 | Novel 3-pyrazolecarboxamide derivatives with cannabinoid receptor affinity | SANOFI SYNTHELABO (FR) | 2001-05-23 | — | — | EP | claimed |
| EP-1878723-B1 | N-[(1,5-diphenyl-1H-pyrazol-3-yl)methyl]sulfonamide derivatives antagonists of the CB1 cannabinoids receptors | SANOFI AVENTIS (FR) | 2010-05-26 | — | — | EP | disclosed |
| EP-1878723-A1 | N-[(1,5-diphenyl-1H-pyrazol-3-yl)methyl]sulfonamide derivatives antagonists of the CB1 cannabinoids receptors | Sanofi-Aventis (FR) | 2008-01-16 | — | — | EP | disclosed |
| US-6028084-A | Pyrazole derivatives, method for preparing same, and pharmaceutical compositions containing said derivatives | SANOFI-SYNTHELABO (FR) | 2000-02-22 | — | — | US | disclosed |