Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252636 | 0.82 | JAK2 (0.39) | MEN1KMT2AALDH1A1MAPTPDE4B | |
| SCHEMBL3246092 | 0.80 | MEN1 (0.39) | MEN1KMT2AALDH1A1MAPTPDE4B | |
| SCHEMBL3247572 | 0.76 | MEN1 (0.36) | MEN1KMT2AALDH1A1MAPTPDE4B | |
| SCHEMBL23249978 | 0.75 | RECQL (0.47) | MEN1KMT2AALDH1A1MAPTGPR119 | |
| SCHEMBL22973125 | 0.72 | RECQL (0.44) | MEN1KMT2AALDH1A1MAPTPDE4B | |
| SCHEMBL21458845 | 0.72 | RECQL (0.44) | MEN1KMT2AALDH1A1MAPTPDE4B | |
| SCHEMBL23910164 | 0.71 | NR1H2 (0.42) | MEN1KMT2AALDH1A1MAPTPDE4B | |
| SCHEMBL23860091 | 0.71 | NR1H2 (0.42) | MEN1KMT2AALDH1A1MAPTPDE4B | |
| SCHEMBL3247963 | 0.70 | MAPT (0.40) | MEN1KMT2AALDH1A1MAPTGPR119 | |
| SCHEMBL1018270 | 0.69 | NR1H2 (0.48) | MEN1KMT2AALDH1A1MAPTPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799674-B1 | NEW PIPERIDINE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-05-05 | — | — | EP | disclosed |